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Archives of Anesthesiology and Critical Care، جلد ۴، شماره ۳، صفحات ۴۹۷-۵۰۰
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Effect of Ketamine-Sufentanil and Ketamine-Midazolam to induce sedation and analgesia in Pediatric with Lumbar Puncture or Bone Marrow Aspiration |
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| چکیده انگلیسی مقاله |
Background: The combination of sedative and analgesic drugs has a favorable effect on pain management and sedation during painful procedures in pediatrics. Therefore, our aim was to compare the effect of sedation and analgesia of ketamine-sufentanil and ketamine-midazolam in painful procedures in children with blood malignancies. Methods: This double-blind, clinical trial was performed on 82 children with malignancy who had indication of painful diagnostic intervention; patients were randomly divided into two groups of ketamine-sufentanil (KS) and ketamine -midazolam (KM). In KS group, sufentanil 0.5mcg/ kg and ketamine 1mg/ kg and in the KM group, ketamine 1mg/ kg, and midazolam 0.1mg/ kg bolus were prescribed. In either group, hemodynamic indicators of sedation, side effects, duration of effectiveness were recorded. Data were analyzed using SPSS 20. Results: Sedation based on Ramsay sedation score was not significantly different between the two groups (p= 0.39). The average recovery time in the midazolam-ketamine group was higher (p-value= 0.076). Conclusion: The combination of ketamine-sufentanil and ketamine-midazolam was effective in sedation and analgesia in bone marrow aspiration and lumber puncture; side effects were however, lower in ketamine-midazolam group. |
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| کلیدواژه‌های انگلیسی مقاله |
ketamine,sufentanil,midazolam,pediatric |
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| نویسندگان مقاله |
| Hamidreza Shetabi
Isfahan University of Medical Sciences
| Amir Shafa
Department of Anesthesia, Al-Zahra Medical Center, Isfahan, Iran.
| Mohamadmehdi Zare
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| نشانی اینترنتی |
http://aacc.tums.ac.ir/index.php/aacc/article/view/179 |
| فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/371/article-371-684514.pdf |
| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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| نوع مقاله منتشر شده |
Research Article(s) |
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