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Iranian Biomedical Journal، جلد ۲، شماره ۱، صفحات ۳۹-۳۴
عنوان فارسی Effect of Passive Immunization with Specific Anti-FSH on Tes- ticular Lipids and Some Lipogenic Enzymes of Adult Bonnet Monkeys
چکیده فارسی مقاله The effect of anti-follicular stimulating hormone (FSH) on testicular lipid and the specific activity of testicular enzymes of the isocitrate dehydrogenase (ICDH), pyruvate/malate dehydrogenase (MDH) and malic enzyme involved in lipogenesis were studied in mature bonnet monkeys, Macaca radiata. Immunization of monkey with anti-FSH for 24 days did not produce any significant changes in the body weight, organ weight and pituitary weight. Testicular isocitrate dehydrogenase (ICDH) and malic enzyme activities were decreased significantly but MDH activity was stimulated by anti-FSH treatment. Testicular total lipid, phospholipid and cholesterol, were not altered significantly by the Anti-FSH treatment. Increased level of free cholesterol was also observed after FSH treatment. Among glyceride glycerol sub classes, triacyl glycerol showed a significant increase.Among testicular phospholipid classes, phosphatidyl inositol was markedly decreased by anti-FSH immunization. Data on serum hormonal profile, shows that there were no alteration in serum testosterone, prolactin (PRL) and luteinizing hormones (LH) but FSH was significantly decreased. The present study reveals that immunization with anti-FSH has significant effect on different class Of testicular lipids and pyruvate malate enzymes cycle.
کلیدواژه‌های فارسی مقاله Anti-FSH، lipogenic enzymes، passive immunization
عنوان انگلیسی Effect of Passive Immunization with Specific Anti-FSH on Tes- ticular Lipids and Some Lipogenic Enzymes of Adult Bonnet Monkeys
چکیده انگلیسی مقاله The effect of anti-follicular stimulating hormone (FSH) on testicular lipid and the specific activity of testicular enzymes of the isocitrate dehydrogenase (ICDH), pyruvate/malate dehydrogenase (MDH) and malic enzyme involved in lipogenesis were studied in mature bonnet monkeys, Macaca radiata. Immunization of monkey with anti-FSH for 24 days did not produce any significant changes in the body weight, organ weight and pituitary weight. Testicular isocitrate dehydrogenase (ICDH) and malic enzyme activities were decreased significantly but MDH activity was stimulated by anti-FSH treatment. Testicular total lipid, phospholipid and cholesterol, were not altered significantly by the Anti-FSH treatment. Increased level of free cholesterol was also observed after FSH treatment. Among glyceride glycerol sub classes, triacyl glycerol showed a significant increase.Among testicular phospholipid classes, phosphatidyl inositol was markedly decreased by anti-FSH immunization. Data on serum hormonal profile, shows that there were no alteration in serum testosterone, prolactin (PRL) and luteinizing hormones (LH) but FSH was significantly decreased. The present study reveals that immunization with anti-FSH has significant effect on different class Of testicular lipids and pyruvate malate enzymes cycle.
کلیدواژه‌های انگلیسی مقاله Anti-FSH, lipogenic enzymes, passive immunization
نویسندگان مقاله محمد ارجمند | mohammad arjmand


p govindarajulu | m michael aruldhas


m michael aruldhas | p. govindarajulu


نشانی اینترنتی http://ibj.pasteur.ac.ir/browse.php?a_code=A-10-1-460&slc_lang=en&sid=en
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