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Medical Laboratory Journal، جلد ۱۱، شماره ۶، صفحات ۷-۱۱
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Antibacterial Effect of Silver Nanoparticles along with L-Arginine against P. aeruginosa |
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| چکیده انگلیسی مقاله |
ABSTRACT Background and Objectives: Nowadays, the prevalence of multidrug-resistant pathogens such as Pseudomonas aeruginosa is increasing worldwide. Many studies have been seeking new treatment strategies to treat infections caused by these microorganisms. Silver nanoparticles (AgNPs) along with L-arginine have significant antimicrobial effects and could be used as alternatives for ineffective drugs. Methods: In this study, the antibacterial activity of AgNPs, L-arginine and various concentrations of AgNPs along with L-arginine (12.5 and 25 mg/ml) were investigated against P. aeruginosa PAO1 using the broth microdilution method. Results: Minimum inhibitory concentration of AgNPs, L-arginine and AgNPs combined with 25 and 12.5 mg/ml L-arginine was 15.6 μg/ml, 25 mg/ml, 1.9 μg/ml and 3.9 μg/ml, respectively. Minimum bactericidal concentration of AgNPs, L-arginine and AgNPs combined with 25 and 12.5 mg/ml L-arginine was 31.6 μg/ml, 50 mg/ml, 3.9 μg/ml and 7.8 μg/ml, respectively. Conclusion: Our study suggests that AgNPs along with L-arginine can be used as an alternative antibacterial agent against P. aeruginosa, and might be useful for treatment of wound infections. Keywords: Nanoparticles, Arginine, Anti-Bacterial Agents, Pseudomonas aeruginosa. |
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| نویسندگان مقاله |
مینا پارسا | mina parsa
department of microbiology, faculty of veterinary medicine, urmia university, urmia, iran
سازمان اصلی تایید شده: دانشگاه ارومیه (Urmia university)
ملاحت احمدی | malahat ahmadi
professor of bacteriology, department of microbiology, faculty of veterinary medicine, urmia university, urmia, iran
سازمان اصلی تایید شده: دانشگاه ارومیه (Urmia university)
حبیب دستمالچی | habib dastmalchi
department of microbiology, faculty of veterinary medicine, urmia university, urmia, iran
سازمان اصلی تایید شده: دانشگاه ارومیه (Urmia university)
علی اصغر تهرانی | aliasghar tehrani
department of pathology, faculty of veterinary medicine, urmia university, urmia, iran
سازمان اصلی تایید شده: دانشگاه ارومیه (Urmia university)
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| نشانی اینترنتی |
http://goums.ac.ir/mljgoums/browse.php?a_code=A-10-1-495&slc_lang=fa&sid=en |
| فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/168/article-168-568721.pdf |
| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
تخصصی |
| نوع مقاله منتشر شده |
تحقیقی |
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