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Medical Laboratory Journal، جلد ۱۱، شماره ۴، صفحات ۱۹-۲۳
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Prevalence of Active Cytomegalovirus Infection in Hemodialysis Patients |
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| چکیده انگلیسی مقاله |
ABSTRACT Background and Objectives: Human cytomegalovirus (HCMV) is the most common viral cause of morbidity and mortality in immunocompromised patients. The aim of this study was to evaluate the frequency of active CMV infection in hemodialysis patients in Gorgan, Iran. Methods: Plasma samples were obtained from 149 hemodialysis patients at Hemodialysis Unit of Panje-Azar Medical Centre in Gorgan, Iran. Presence of CMV-DNA in plasma samples was evaluated by polymerase chain reaction (PCR) using specific primers for highly conserved regions of major capsid protein gene of HCMV. In addition, level of CMV-IgM antibody was measured by serological testing. Demographic information and past medical history of patients were also recorded. Data was analyzed by SPSS software (version 18). Results: Total prevalence of CMV infection was 6.7% (10/149) among the patients receiving hemodialysis. CMV-DNA and anti-CMV IgM antibody were detected in 2.68% and 4.69%, of the samples, respectively. One case was found positive for both CMV-DNA and anti-CMV IgM antibody. CMV infection did not have any correlation with gender, age, ethnicity, duration of hemodialysis, and history of blood transfusion. Conclusion: A notable proportion of hemodialysis patients in Gorgan have active CMV infection. Accurate detection of these individuals is important for preventing infection spread, especially in immunocompromised individuals. Simultaneous diagnosis of CMV infection using serological testing and PCR assay could help reduce the risk of infection spread. Keywords: HCMV, Hemodialysis, PCR, Iran. |
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| کلیدواژه‌های انگلیسی مقاله |
HCMV, Hemodialysis, PCR, Iran. |
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| نویسندگان مقاله |
میشار کلیشادی | mishar kelishadi
student research committee, department of microbiology, golestan university of medical sciences, gorgan, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی گلستان (Golestan university of medical sciences)
محمد موجرلو | mohammad mojerloo
department of hemodialysis, 5th azar hospital, gorga, iran
پژمان هاشمی | pezhman hashemi
student research committee, department of microbiology, golestan university of medical sciences, gorgan, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی گلستان (Golestan university of medical sciences)
سبحان صمدی | sobhan samadi
student research committee, department of microbiology, golestan university of medical sciences, gorgan, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی گلستان (Golestan university of medical sciences)
علیجان تبرایی | alijan tabarraei
infectious diseases research center, department of microbiology، golestan university of medical sciences, gorgan, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی گلستان (Golestan university of medical sciences)
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| نشانی اینترنتی |
http://goums.ac.ir/mljgoums/browse.php?a_code=A-10-1-470&slc_lang=fa&sid=en |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
تخصصی |
| نوع مقاله منتشر شده |
تحقیقی |
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