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Iranian Journal of Kidney Diseases، جلد ۶، شماره ۳، صفحات ۲۰۳-۰
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عنوان انگلیسی Differences in Cardiovascular Disease Risk Factors Associated With Maximum and Mean Carotid Intima-Media Thickness Among Hemodialysis Patients
چکیده انگلیسی مقاله Normal 0 false false false EN-US X-NONE AR-SA /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman","serif";} Introduction. Carotid intima-media thickness (CIMT) could be used as a surrogate marker of atherosclerosis in hemodialysis patients. Since different mechanisms are involved in the atheroma formation and arterial wall thickness, we assessed the relationship between the maximum and the mean CIMT with different cardiovascular risk factors in dialysis patients. Materials and Methods. The mean and the maximum CIMT were measured using a B-mode ultrasonography in 75 hemodialysis patients, and the correlation between CIMT and cardiovascular risk factors were assessed. Results. The mean and maximum CIMT measurements were 0.5 mm (range, 0.2 mm to 1 mm) and 3.4 mm (1.4 mm to 5.6 mm), respectively. Among all the studied variables, age ( P = .04, r = 0.238), HS-CRP ( P = .01, r = 0.284), mean arterial blood pressure ( P = .003, r = 0.343), and DM ( P = .02) had significant correlations with the mean CIMT, while only age ( P = .02, r = 0.473) and serum creatinine levels ( P = .02, r = -0.493) were significantly associated with the maximum CIMT. A positive nonsignificant correlation was observed between the mean and maximum CIMT values ( P = .08, R 2 linear = 0.214). Conclusions. These findings suggest that in dialysis patients, effects of cardiovascular risk factors on the mean and maximum CIMT might be different. Further studies are recommended to evaluate the prediction impact of each risk factor in end-stage renal disease patients compared with otherwise healthy individuals.
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نویسندگان مقاله امیر احمد نصیری | amir ahmad nassiri


منیرالسادات حاکمی | monirsadat hakemi


رضا اسدزاده | reza asadzadeh


علی محمد فیضی | ali mohammad faizei


سودابه اعلاتاب | sudabeh alatab


رضا میری | reza miri


مهدی یاسری | mehdi yaseri


نشانی اینترنتی http://www.ijkd.org/index.php/ijkd/article/view/664
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده ORIGINAL | Dialysis
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