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Iranian Endodontic Journal، جلد ۱۱، شماره ۲، صفحات ۸۵-۹۰

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عنوان انگلیسی Human Pulp Response to Direct Pulp Capping and Miniature Pulpotomy with MTA after Application of Topical Dexamethasone: A Randomized Clinical Trial
چکیده انگلیسی مقاله Introduction: The aim of this randomized clinical trial was to compare the histologic pulp tissue response to one-step direct pulp capping (DPC) and miniature pulpotomy (MP) with mineral trioxide aggregate (MTA) after application of dexamethasone in healthy human premolars. Methods and Materials: Forty intact premolars from 10 orthodontic patients, were randomly chosen for DPC ( n =20) or MP ( n =20). In 10 teeth from each group, after exposure of the buccal pulp horn, topical dexamethasone was applied over the pulp. In all teeth the exposed/miniaturely resected pulp tissue was covered with MTA and cavities were restored with glass ionomer. Teeth vitality was evaluated during the next 7, 21, 42, and 60 days. Signs and/or symptoms of irreversible pulpitis or pulp necrosis were considered as failure. According to the orthodontic schedule, after 60 days the teeth were extracted and submitted for histological examination. The Kruskal-Wallis and Fisher’s exact tests were used for statistical analysis of the data ( P =0.05). Results: Although dexamethasone specimens showed less inflammation, calcified bridge, pulpal blood vasculature, collagen fibers and granulation tissue formation were not significantly different between the groups ( P >0.05). Conclusion: Topical dexamethasone did not hindered pulp healing but reduced the amount of underlying pulpal tissue inflammation after DPC and MP in healthy human premolars.
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نویسندگان مقاله سید امیر موسوی | seyed amir mousavi


جمیله قدوسی | jamileh ghoddusi


نوشین محتشم | nooshin mohtasham


شیرین شاه ناصری | shirin shahnaseri


پیام paymanpour | payam paymanpour


جون ichiro kinoshita | jun ichiro kinoshita



نشانی اینترنتی http://journals.sbmu.ac.ir/iej/article/view/11548
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Article
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