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International Journal of Pediatrics، جلد ۵، شماره ۱۲، صفحات ۶۵۱۵-۶۵۲۵
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عنوان انگلیسی Prevalence of Nasal Carriage Methicillin-Resistant Staphylococcus aureus with mecA Gene among Healthy Primary School Boys in North of Iran; A Cross-Sectional Study
چکیده انگلیسی مقاله Background: Nasal carriage of Staphylococcus aureus has a key role in the epidemiology and pathogenesis of infection. In this study we aimed to investigate the occurrence of the methicillin resistant Staphylococcus aureus (MRSA )and mecA gene among healthy primary school boys in north of Iran.Material and methods: This cross-sectional study was conducted from January 2017 to July 2017 in Sari located in the north of Iran. Nasal swabs were taken from 277 healthy primary school boys. Staphylococcus aureus strains were identified according to the standard microbiological procedures and presence of spa gene. Agar screen method was used to determine MRSA. All MRSA isolates were examined for the existence of the mecA and spa gene by using Multiplex Polymerase chain reaction (PCR) method.Results: The prevalence of nasal carriage of MRSA was 29.24%. The existence of the mecA gene among MRSA strains was 49.38%. The rate of resistant isolated to Cefoxitin, Vancomycin, Cefixime, Cefalotin, Clindamycin, ,Cefazolin, Co-amoxiclav, Amoxicillin, cotrimoxazole and Cefalexin antibiotics were 48.14%, 39.50%, 98.76%, 96.29%, 54.32%, 91.35%, 97.53%, 95.06%, 7.40% and 100% respectively.Conclusions: The high rate of Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) and presence of mec A gene and resistance to critically antibiotics against MRSA is a therapeutic concern and needs to strategies to prevent community spread of S. aureus.
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نویسندگان مقاله شقایق رضایی | shaghayegh rezai
msc of microbiology, department of biology, islamic azad university, qaemshahr branch, qaemshahr, iran.

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

فاطمه peyravii قادیکلایی | fatemeh peyravii ghadikolaii
assistant professor, department of biology, islamic azad university, qaemshahr branch, qaemshahr, iran.

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

محمد آهنجان | mohammad ahanjan
associate professor, department of microbiology, pediatric infectious diseases research center, mazandaran university of medical sciences, sari, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مازندران (Mazandaran university of medical sciences)

رضا ولدان | reza valadan
assistant professor, molecular and cell biology research center, department of immunology, faculty of medicine, mazandaran university of medical sciences, sari, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مازندران (Mazandaran university of medical sciences)

فاطمه آهنگرکانی | fatemeh ahangarkani
phd student in medical mycology, antimicrobial resistance research center, student research committee, mazandaran university of medical sciences, sari, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مازندران (Mazandaran university of medical sciences)

محمد صادق رضایی | mohammad sadegh rezai
associate professor, pediatric infectious diseases research center, mazandaran university of medical sciences, sari, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مازندران (Mazandaran university of medical sciences)

علی اصغر نادی قرا | ali asghar nadi ghara
phd of biostatistics, department of biostatistics, school of health sciences, mazandaran university of medical sciences, sari, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مازندران (Mazandaran university of medical sciences)

نشانی اینترنتی http://ijp.mums.ac.ir/article_9460.html
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