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Iranian Journal of Basic Medical Sciences، جلد ۱۵، شماره ۴، صفحات ۹۵۸-۹۶۴
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عنوان انگلیسی Effect of Vitamin Supplementation on Serum Oxidized Low-Density Lipoprotein Levels in Male Subjects with Cardiovascular Disease Risk Factors
چکیده انگلیسی مقاله Objective(s) Oxidized low-density lipoproteins (ox-LDLs) appear to play a significant role in atherogenesis. In fact, circulating ox-LDL concentrations have been recognized as a risk factor for cardiovascular disease (CVD). The main objectives of this study were to assess the effects of antioxidant vitamins on ox-LDL as a biomarker of CVD in male subjects with CVD risk factors. Materials and Methods The effect of antioxidant vitamins on ox-LDL as a biomarker of CVD in male subjects with CVD in male subjects with CVD risk factors at baseline and after 12 weeks of supplementation with vitamin E (400 IU), C (500 mg), ß-carotene (15 mg), and the combined supplements (E, C, and ß-carotene) respectively defined as group E, C, B and control group was considered as group P. Results The mean values for ox-LDL at the baseline were 86.93 ± 26.30 U/l in group C, 94.52 ± 38.40 U/l in group E, 79.73±2.07 U/l in group B, 85.97±23.07 U/l in combined group, and 84.90± 14.66 U/l in group P. After 12 weeks of intervention the percentage of changes for group C, group E, group B, COM group, and group P were (-18.32), (-2286), (-17.31), (-19.01) and (-2.0), respectively. Using Wilcoxon method, significant differences were detected in the mean ox-LDL concentrations of baseline and after intervention, values in the C, E, B and combined groups (P< 005). Conclusion This study illustrated that diet supplemented with vitamin C (500 mg), vitamin E (400 IU), ß-carotene (15 mg), and the combination of these vitamins was associated with lower serum ox-LDL levels.
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نویسندگان مقاله سعید نجف پور بوشهری | saeid najafpour boushehri
faculty of health, bushehr university of medical sciences. bushehr, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بوشهر (Bushehr university of medical sciences)

rokiah محمدیوسف | rokiah mohammad yusof
department of nutrition and dietetics. faculty of medicine and health sciences, university putra malaysia, malaysia


محمد نصیر محمد تایب | mohammad nasir mohammad taib
department of nutrition and dietetics. faculty of medicine and health sciences, university putra malaysia, malaysia


کامران میرزایی | kamran mirzaei
faculty of health, bushehr university of medical sciences. bushehr, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بوشهر (Bushehr university of medical sciences)

نرگس یزدخواستی | narges yazdekhasti
isfahan cardiovascular research center, isfahan university of medical sciences. isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

صمد اکبرزاده | samad akbarzadeh
faculty of health, bushehr university of medical sciences. bushehr, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بوشهر (Bushehr university of medical sciences)

نشانی اینترنتی http://ijbms.mums.ac.ir/article_4892.html
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