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Iranian Journal of Public Health، جلد ۴۱، شماره ۱، صفحات ۹-۱۶

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عنوان انگلیسی Family History and Prior Allergies of Cancers and the Risk of Adult Leukemia in Shandong Province, China
چکیده انگلیسی مقاله Background: A case-control study was carried out to investigate the roles of prior allergies and family history of cancers and their interaction in the etiology of adult leukemia. Methods: Prior allergies status and family history of cancers in first-degree relatives were compared between 131 incident leukemia cases and 206 hospital-based controls. Odds ratios (OR) were estimated using an unconditional regression model taking into account potential confounding factors. Results: Significant association between adult leukemia and prior allergies and family history of cancer (OR=2.09, 95% CI: 1.22-3.58 for prior allergies; and OR=2.35, 95% CI: 1.09-5.03 for family history of cancer, OR=15.88, 95% CI: 1.77-142.55 for both the two factors (+), respectively) was found after adjusting for potential confounding factors. Conclusion: Prior allergies and family history of cancers may be risk factors for adult leukemia; their interaction was likely to be synergistic rather than additive for the risk of leukemia.
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نویسندگان مقاله hc ونگ | hc wang
dept. of hematology, qilu hospital, shandong university, jinan, shandong, china


hl lin | hl lin
school of public health and primary care, the chinese university of hong kong, shatin, nt, hong kong


n شایو | n shao
dept. of hematology, qilu hospital, shandong university, jinan, shandong, china


jr زانگ | jr zhang
dept. of hematology, qilu hospital, shandong university, jinan, shandong, china


j zou | j zou
dept. of hematology, qilu hospital, shandong university, jinan, shandong, china


cy ji | cy ji
dept. of hematology, qilu hospital, shandong university, jinan, shandong, china



نشانی اینترنتی http://ijph.tums.ac.ir/index.php/ijph/article/view/2628
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