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Iranian Journal of Public Health، جلد ۴۶، شماره ۹، صفحات ۱۱۶۷-۱۱۷۵
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Bulge Region as a Putative Hair Follicle Stem Cells Niche: A Brief Review
چکیده انگلیسی مقاله Background: Hair follicle stem cells exist in different sites. Most of the hair follicle stem cells are reside in niche called bulge. Bulge region is located between the opening of sebaceous gland and the attachment site of the arrector pili muscle. Methods: Data were collected using databases and resources of PubMed, Web of Science, Science Direct, Scopus, MEDLINE and their references from the earliest available published to identify English observational studies on hair follicle bulge region. Results: Bulge stem cells are pluripotent with high proliferative capacity. Specific markers allow the bulge cells to be isolated from mouse or human hair follicle. Stem cells isolated from bulge region are label retaining and slow cycling hence these cells are defined as label-retaining cells. Bulge cell populations, due to their plasticity nature are able to differentiate into distinct linage and could contribute in tissue regeneration. Conclusion: The current review discuss about bulge stem cells characteristics and biology including their cycle, location, plasticity, specific markers and regenerative nature. Also the differences between mouse and human hair follicles are investigated.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله ساناز joulai veijouye | sanaz joulai veijouye
physiology research center, iran university of medical sciences, tehran, iran dept. of biology, university campus 2, university of guilan, rasht, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)

اباذر یاری | abazar yari
dept. of anatomy, school of medicine, alborz university of medical sciences, karaj, iran


فاطمه حیدری | fatemeh heidari
dept. of anatomy, school of medicine, qom university of medical sciences, qom, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی قم (Qom university of medical sciences)

نیره ساجدی | nayereh sajedi
dept. of anatomy, school of medicine, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

فاطمه غرقی مغانی | fatemeh ghoroghi moghani
dept. of anatomy, school of medicine, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

ملیحه نوبخت | maliheh nobakht
physiology research center, iran university of medical sciences, tehran, iran dept. of anatomy, school of medicine, isfahan university of medical sciences, isfahan, iran anti-microbial resistance research center, iran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

نشانی اینترنتی http://ijph.tums.ac.ir/index.php/ijph/article/view/10987
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/86/article-86-426960.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Review Article(s)
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