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Journal of Research in Medical Sciences، جلد ۲۲، شماره ۳، صفحات ۰-۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Appropriate blood component therapy can reduce postcardiac surgery acute kidney injury through packed cell transfusion reduction
چکیده انگلیسی مقاله Background: Acute kidney injury (AKI) can happen due to different factors such as anemia. Packed cell (PC) transfusion is an important cause of AKI occurrence. Te aim of the study is to investigate whether appropriate blood component (BC) therapy can reduce blood transfusion and it would result in AKI decreasing. Materials and Methods: We conducted a cohort study of 1388 patients who underwent cardiac surgery in one university hospital. A serum creatinine higher than 2 mg/dl, renal disease history, renal replacement therapy (chronic dialysis) were our exclusion criteria. Results : from our 1088 samples, 701 (64.43%) patients had normal kidney function, 277 (25.45%) were in the AKI-1 group, 84 (7.72%) had an AKI-2 function, and the rest of patients were classified as end stage. A mean of more than three PC units were transfused for the second and third stage of AKI, which was significantly higher than other AKI groups ( P = 0.009); this higher demand of blood product was also true about the fresh frozen plasma, platelet, and fibrinogen. However, there were no needs of fibrinogen in the patients with normal kidney function. Te cardiopulmonary bypass time had an average of 142 ± 24.12, which obviously was higher than other groups ( P = 0.032). Total mortality rate was 14 out of 1088 (1.28%), and expiration among the AKI stages 2 and 3 was meaningfully ( P = 0.001) more than the other groups. Conclusion: A more occurrence of AKI reported for the patients who have taken more units of blood. However, BC indicated to be safer for compensating blood loss because of low AKI occurrence among our patients. Key words: Anesthesia, creatinine, whey protein supplements
کلیدواژه‌های انگلیسی مقاله Anesthesia, creatinine, whey protein supplements
نویسندگان مقاله کیانوش صابری | kianoush saberi
imam khomeini medical and research center tehran university of medical sciences imam khomeini medical and research center tehran iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

مهرداد صالحی | mehrdad salehi
imam khomeini medical and research center tehran university of medical sciences imam khomeini medical and research center tehran iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

مهرزاد رحمانیان | mehrzad rahmanian
imam khomeini medical and research center tehran university of medical sciences imam khomeini medical and research center tehran iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

علی رضا بخشنده | ali reza bakhshandeh
imam khomeini medical and research center tehran university of medical sciences imam khomeini medical and research center tehran iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

غلام رضا معصومی | gholam reza massoumi
anesthesiology school of medicine, isfahan university of medical sciences nour amp;amp; aliasghar hospital

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/10663
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/218/article-218-421751.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Short Communications
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