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Journal of Medical Bacteriology، جلد ۶، شماره ۱-۲، صفحات ۲۱-۲۷
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Evaluation of the Antibacterial Effects of Nickel Nanoparticles on Biofilm Production by Streptococcus mutans
چکیده انگلیسی مقاله Background : Dental caries is a biofilm-dependent disease mainly causes by cariogenic bacteria that colonize dental surfaces, especially Streptococcus mutans . Nickel is a safe metal element which routinely used in dental compounds. The antibacterial and anti-biofilm effects of nickel nanoparticles (Ni-NPs) have been determined in limited studies, but the anti-biofilm effects of Ni-Nps on S . mutans have not been investigated before, so this study was aimed to investigate the anti-biofilm effects of Ni-NPs on S. mutans ATCC 35668. Methods : Biofilm formation by S. mutans ATCC 35668 was assayed by Microtiter Dish Biofilm Formation Assay and absorbance was measured by ELISA reader at 550 nm. The amounts of biofilm formation were also measured in the presence of 1, 01 and 0.01mg/mL concentrations of Ni- NPs by the same protocol and the mean amounts were compared between groups. Eight replicates were considered for each experiment. Data was statistically analyzed by SPSS16 software. Results : According to the statistical analysis, the amounts of biofilm formation were significantly reduced in the presence of all the tested concentrations of Ni-NPs. Conclusion : The current findings showed the potent anti-biofilm effects of Ni-NPs even in a concentration as low as 0.01 mg/ mL, so it is proposed for different applications in dentistry, considering its anti-biofilm effects. However, further studies on other biofilm producing members of oral microbiota including Lactobacilli are recommended.
کلیدواژه‌های انگلیسی مقاله Biofilm, Nickel nanoparticles, Streptococcus mutans.
نویسندگان مقاله نازنین حبیبی | nazanin habibi
students research committee, urmia university of medical sciences, urmia, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ارومیه (Urmia university of medical sciences)

نیما حسینی جزنی | nima hosseini jazani
department of microbiology, faculty of medicine, urmia university of medical sciences, urmia, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ارومیه (Urmia university of medical sciences)

صابر یوسفی | saber yousefi
department of microbiology, faculty of medicine, urmia university of medical sciences, urmia, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ارومیه (Urmia university of medical sciences)

نشانی اینترنتی http://jmb.tums.ac.ir/index.php/jmb/article/view/298
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/313/article-313-414668.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Articles
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