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مجله تغذیه و امنیت غذایی، جلد ۲، شماره ۲، صفحات ۱۶۵-۱۷۲

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عنوان انگلیسی Effect of Oral Supplementation of L-arginine on Sexual Function in Men with Type 2 Diabetes: A Double-blind Clinical Trial
چکیده انگلیسی مقاله Background: Sexual dysfunction is an important health problem which prevalence in patients with type 2 diabetes (T2D) is higher than other people. The aim of this study was to evaluate the effect of L-arginine oral supplementation on sexual function in men with T2D and mild-to-moderate erectile dysfunction (ED). Methods: Eighty men with T2D, suffering from mild-to-moderate erectile dysfunction participated in this double-blind clinical trial. They were randomly assigned in to two groups; receiving 5 g/day L-arginine (AG) or placebo group (PG) for 4 weeks. Sexual functions were recorded with international index of erectile function questionnaire at the beginning and end of the intervention. Total testosterone concentrations were measured too. Results: The total mean score of sexual function parameters significantly increased only in AG than PG (43.2 ± 6.2 vs. 39.4 ± 4.0, P = 0.003). Against PG, the mean of all parameters significantly improved in AG after intervention. Only the mean score of erectile function in AG had a significant increase compared to PG. Mean of other sexual activity scores between the two groups had no significant differences. The mean of testosterone concentration had a significant increase in both groups after the intervention, but the mean of changes was significantly higher in AG than in PG (1.91 μg/L vs. 0.53 μg/L, P = 0.004). Conclusions: The present trial showed that daily consumption of 5 g L-arginine for four weeks in T2D men with mild-to-moderate sexual dysfunction improved various parameters such as erectile function, sexual satisfaction, sexual desire, pleasure from sexual intercourse, and testosterone level.
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نویسندگان مقاله حسن مظفری خسروی | hassan mozaffari khosravi
department of nutrition, school of public health, shahid sadoughi university of medical sciences, yazd, iran


مصیب فلاحی | mosayeb fallahi


محمد افخمی اردکانی | mohammad afkhami ardekani



نشانی اینترنتی http://jnfs.ssu.ac.ir/browse.php?a_code=A-10-1-31&slc_lang=fa&sid=en
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زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده public specific
نوع مقاله منتشر شده orginal article
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