Veterinary Research Forum، جلد ۸، شماره ۲، صفحات ۱۴۵-۱۵۳
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عنوان انگلیسی Therapeutic effects of marshmallow (Althaea officinalis L.) extract on plasma biochemical parameters of common carp infected with Aeromonas hydrophila
چکیده انگلیسی مقاله This study evaluated preclinical and clinical safety of marshmallow (Althaea officinalis L.) extract as a naturopathic medicine in common carp deliberately infected with Aeromonas hydrophila. The fish were fed 0 (control), 2.50, 5.00 and 10.00 g of marshmallow extract for 60 days in a preclinical experiment and then, challenged with A. hydrophila for a 10-day experiment. Significant increases were observed in aspartate aminotransferase (AST), lactate dehydrogenase (LDH), alkaline phosphatase (ALP), creatine phosphokinase (CPK) activities and plasma creatinine levels in fish fed 10 g marshmallow extract per kg feed. However, alanine aminotransferase (ALT) significantly decreased on day 60. The fish fed 2.50 g marshmallow extract per kg feed indicated increased levels of total protein and globulin. There were no significant changes in albumin levels (p > 0.05). 2.50 and 5.00 g marshmallow significantly decreased triglyceride and cholesterol levels and increased glucose levels (p < 0.05). A. hydrophila significantly increased AST, ALT, LDH, ALP and CPK activities and plasma glucose, cholesterol, triglycerides and creatinine levels after 10 days (p < 0.05). Total plasma protein, albumin and globulin levels in fish challenged with A. hydrophila were significantly lower than the control group (p < 0.05). Marshmallow extract at 5.00 and 10.00 g can adjust plasma biochemical parameters in fish challenged with A. hydrophila. The results of preclinical studies and pharmaceutical toxicity of marshmallow extract revealed that dietary levels lower than 5.00 g were safe and effective. The results of this clinical study demonstrated that marshmallow extract (5.00 g kg-1 feed) can protect fish against A. hydrophila.
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نویسندگان مقاله مهدی بنایی |
department of aquaculture, faculty of environment and natural resources, behbahan khatam al-anbia university of technology, behbahan, iran

وحید سلیمانی |
department of aquaculture, faculty of environment and natural resources, behbahan khatam al-anbia university of technology, behbahan, iran

بهزاد نعمت دوست حقی | nematdoost haghi
department of aquaculture, faculty of environment and natural resources, behbahan khatam al-anbia university of technology, behbahan, iran

نشانی اینترنتی http://vrf.iranjournals.ir/article_25822_4c27bfdfab56d0d0c4fc9804c0e9876b.pdf
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/544/article-544-404007.pdf
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زبان مقاله منتشر شده en
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