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مجله علوم اعصاب شفای خاتم، جلد ۵، شماره ۲، صفحات ۱۲۲-۱۲۲
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| عنوان فارسی |
P ۹۱: The Evaluation of Serum Level of ۲۵-Hydroxy Vitamin D in Patients under Sodium Valproate Medication |
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| چکیده فارسی مقاله |
لطفاً به چکیده انگلیسی مراجعه شود. |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
P 91: The Evaluation of Serum Level of 25-Hydroxy Vitamin D in Patients under Sodium Valproate Medication |
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| چکیده انگلیسی مقاله |
Epilepsy is one of the common neurologic disorders in children. Drug side-effects are one of the important problems in treating patients with epilepsy. Using the antiepileptic medication may cause different side effects such as disorder in bone and vitamin D metabolism. Sodium valproate is one of the antiepileptic medications used widely. Some of its side effects include digestive disorder, increasing of level hepatic enzymes, fatal hepatitis, decreasing level of vitamin D, and etc. The evaluation of serum level of 25-hydroxy vitamin D in patients who are treated with sodium valproate for a long time and presenting suggestions to decrease its side effects. This review study is performed by searching valid internal and external scientific databases (Science Direct, PubMed ‚Google scholar, SID and etc.) by related keywords. Recent researches have shown that antiepileptic medications including sodium valproate commonly cause a decrease in vitamin D level. Also, decrease in the measurement of bone marrow density (BMD) in patients treating with sodium valproate for a long time has been proved. So, periodic measurement of the level of 25-hydroxy vitamin D in children with epilepsy who were treated with sodium valproate is suggested. Also, consuming prophylactic vitamin D is necessary for these patients. Considering the mentioned side effects, it is suggested that this drug should not be consumed by children under 2 year old and pregnant women. |
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| کلیدواژه‌های انگلیسی مقاله |
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| نویسندگان مقاله |
سپیده منصوری مجوفردی | sepideh mansoori majoofardi
a. student research committee‚ facuilty of medicine‚ islamic azad university‚ mashhad branch‚ mashhad, iran b. gastric cancer research group‚ mashhad university of medical science‚ mashhad‚ iran
سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)
زهرا sheidae مهنه | zahra sheidae mehne
student research committee‚ facuilty of medicine‚ islamic azad university‚ mashhad branch‚ mashhad, iran
سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)
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| نشانی اینترنتی |
http://shefayekhatam.ir/browse.php?a_code=A-10-24-941&slc_lang=en&sid=fa |
| فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/337/article-337-393395.pdf |
| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
fa |
| موضوعات مقاله منتشر شده |
تحقیقات پایه در علوم اعصاب |
| نوع مقاله منتشر شده |
مروری |
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