این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
مجله علوم اعصاب شفای خاتم، جلد ۵، شماره ۲، صفحات ۹۴-۹۴
عنوان فارسی P ۶۳: Role of Neuroinflammation in Depression
چکیده فارسی مقاله لطفاً به چکیده انگلیسی مراجعه شود.
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی P 63: Role of Neuroinflammation in Depression
چکیده انگلیسی مقاله The prevalence of mental health disorders continues to rise worldwide, such that it is estimated that 1in 4 individuals will be affected by a mental health disorder at some point in their lifetime. Research has found that the most prevalent mental health disorders are depressive disorder. Depression is a common condition, particularly within the aging population. The development of depression, multifactorial disorder with the signing of neuroinflammatory, appears to be associated with the body allostasis disorder. Research has linked neuroinflammation as a major contributing factor to depression diseases. Recent findings link between inflammation and depression and hypothalamic-pituitary-adrenal particular role (HPA) axis in depression have created. This article reviews the clinical and experimental studies investigating the role of axis HPA, HPA hyperactivity (resulting in increased levels of cortisol), as well as pro-inflammatory cytokine tumor necrosis factor, C-reactive protein and interleukins, in depressed patients. The main reason neuroinflammation effects on depression show lie within the dysregulation of the control and release of pro- and anti-inflammatory cytokines. This can come from an internal or external insult to the system, or from changes in the individual due to aging which peaking in immune dysregulation. The need to reduce neuroinflammation has led to extensive research into neuroprotectants. We discuss the efficacy found with nicotine, alcohol, resveratrol, curcumin, and ketamine. Our main focus will be on what research tells us about the connections between neuroinflammation and depression, and the hope that neuroprotectants research gives people suffering from depression stemming from neuroinflammation.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله مریم moghadamqaeini | maryam moghadamqaeini
student research committee, facuilty of medicine, islamic azad university, mashhad branch, mashhad, iran

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

زهرا sheidae مهنه | zahra sheidae mehne
student research committee, facuilty of medicine, islamic azad university, mashhad branch, mashhad, iran

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

فاطمه moghadamqaeini | fatemeh moghadamqaeini
student research committee, facuilty of medicine, islamic azad university, mashhad branch, mashhad, iran

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

نشانی اینترنتی http://shefayekhatam.ir/browse.php?a_code=A-10-24-913&slc_lang=en&sid=fa
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/337/article-337-393367.pdf
کد مقاله (doi)
زبان مقاله منتشر شده fa
موضوعات مقاله منتشر شده تحقیقات پایه در علوم اعصاب
نوع مقاله منتشر شده مروری
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات