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Iranian Journal of Parasitology، جلد ۷، شماره ۱، صفحات ۹۲-۹۶
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عنوان انگلیسی Novel in Vitro Efficiency of Chitosan Biomolecule against Trichomonas gallinae
چکیده انگلیسی مقاله Background : Development of new natural agents for parasitic diseases treatment has unexpec­tedly increased to overcome effectively against emergence and re-emergence of parasitic diseases, the appearance of drug resistant organisms and toxic side effects of current agents. The aim of the study was to evaluate antiprotozoal activities of chitosan biomolecule on trophozoites of Trichomo­nas gallinae . Methods : The antitrichomonal activity of various low molecular weight chitosan concentrations including 125, 250, 500 and 1250 μg ml -1 against T. gallinae trophozoites cultured in trypticase-yeast extract-maltose medium supplemented with heat-inactivated cold horse serum was eva­luated in vitro. Samples containing medium without chitosan were also assayed as controls. Results : The mortality rates at 0, 3 and 6 h post treatment with all concentrations were signifi­cantly different from control group ( P< 0.05). Treated trophozoites showed more susceptibility to the highest concentration reaching mortality rate of 100% at 3h post inoculation. However, at this time, results for 125, 250 and 500 μg ml -1 were 93%, 95% and 96.7%, respectively. Conclusion : The results demonstrate that the application of chitosan biomolecule is a promising option for treatment of trichomoniasis in pigeons.
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نویسندگان مقاله دکتر مرضیه | m tavassoli
department of pathobiology, faculty of veterinary medicine, urmia university, urmia, iran

سازمان اصلی تایید شده: دانشگاه ارومیه (Urmia university)

ایمانی | a imani
department of pathobiology, faculty of veterinary medicine, urmia university, urmia, iran

سازمان اصلی تایید شده: دانشگاه ارومیه (Urmia university)

h تاجیک | h tajik
department of food science and technology, ahar faculty of agriculture, university of tabriz, tabriz, iran

سازمان اصلی تایید شده: دانشگاه تبریز (Tabriz university)

محمود مرادی | m moradi
department of food science and technology, ahar faculty of agriculture, university of tabriz, tabriz, iran

سازمان اصلی تایید شده: دانشگاه تبریز (Tabriz university)

sh پورسید | sh pourseyed
department of pathobiology, faculty of veterinary medicine, urmia university, urmia, iran

سازمان اصلی تایید شده: دانشگاه ارومیه (Urmia university)

نشانی اینترنتی http://ijpa.tums.ac.ir/index.php/ijpa/article/view/226
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