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Iranian Journal of Parasitology، جلد ۷، شماره ۴، صفحات ۴۹-۵۶
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عنوان انگلیسی Human Visceral Leishmaniasis in Kermanshah Province, Western Iran, During 2011-2012
چکیده انگلیسی مقاله Background: Visceral leishmaniasis (VL) or kala-azar is a parasitic disease caused by the species of Leishmania donovani complex . It is endemic in some parts of provinces of Iran. According to the reported cases of VL in Kermanshah Province in recent years, this study was conducted to determine the seroprevalence of VL in high risk villages of the province. Methods: Totally, 1622 serum samples obtained from children under 15 years old and 178 from adults in 22 villages of studied areas. Serum samples were examined by direct agglutination test (DAT) for the detection of anti- Leishmania antibodies. Data were analyzed using SPSS software ver.11.5. Results: Only 6 serum samples (0.33%) showed anti- Leishmania antibodies against L.infantum at titers ≥1/3200. Four of the seropositive cases had a history of kala-azar and Leishman bodies were seen in their bone marrows. The highest (0.5%) and lowest (0.29%) seroprevalence was seen in the age groups of 5-9 and 10-14 years old, respectively. None of the adults were seropositive. There were not any significant differences be-tween the rate of seropositivity in males (0.36%) and females (0.31%). 66.7% of seropositive individuals showed clinical manifestations. The most important symptoms in Kala-azar patients were fever, hepato- spleenomegally and anemia. Conclusion: Kala-azar is occurred sporadically in Kermanshah Province. But presence of significant number of positive sera confirms the necessity for attention of people and clinicians to kala-azar.
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نویسندگان مقاله y حمزوی | y hamzavi
department of medical parasitology and mycology, school of medicine, kermanshah university of medical sciences, kermanshah, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمانشاه (Kermanshah university of medical sciences)

b حمزه | b hamzeh
department of statistic amp;amp; epidemiology, school of public health, kermanshah university of medical sciences, kermanshah, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمانشاه (Kermanshah university of medical sciences)

m محبعلی | m mohebali
department of medical parasitology and mycology, school of public health, tehran university of medical sciences, tehran, iran and center for research of endemic parasites of iran crepi , tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

b آخوندی | b akhoundi
department of medical parasitology and mycology, school of public health, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

kh آژنگ | kh ajhang
province health center, kermanshah university of medical sciences, kermanshah, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمانشاه (Kermanshah university of medical sciences)

خادمی | n khademi
province health center, kermanshah university of medical sciences, kermanshah, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمانشاه (Kermanshah university of medical sciences)

k قدیری | k ghadiri
department of pediatrics, school of medicine, kermanshah university of medical sciences, kermanshah, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمانشاه (Kermanshah university of medical sciences)

h بشیری | h bashiri
department of internal medicine, school of medicine, kermanshah university of medical sciences , kermanshah, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمانشاه (Kermanshah university of medical sciences)

m pajhouhan | m pajhouhan
laboratory sciences, kermanshah university of medical sciences, kermanshah, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمانشاه (Kermanshah university of medical sciences)

نشانی اینترنتی http://ijpa.tums.ac.ir/index.php/ijpa/article/view/283
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