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Iranian Journal of Parasitology، جلد ۸، شماره ۳، صفحات ۴۳۰-۴۳۶
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عنوان انگلیسی Cutaneous leishmaniasis in suspected patients referred to the center for research and training in skin diseases and leprosy, tehran, iran from 2008 to 2011.
چکیده انگلیسی مقاله Background: Cutaneous leishmaniasis (CL) is a major health problem in many parts of Iran, although diagnosis of CL especially in the endemic area is easy, but treatment and management of the disease is a global dilemma. Diag-nosis of CL in non-endemic area is not as simple as in endemic foci. In this study, the status and the proportions of CL induced by Leishmania major and L. tropica among CL suspected patients referred to the Center for Research and Training in Skin Diseases and Leprosy, (CRTSDL) during 2008 to 2011 are described. Methods : CL patients with suspected lesions were clinically examined. History of trip to zoonotic CL and/or anthroponotic CL endemic areas and the char-acteristics of their lesion(s) were recorded. Diagnosis of the lesion was done using direct smear microscopy, culture and conventional polymerase chain reaction (PCR). Results: A total of 404 (M=256, F=148) patients with 776 lesions were re-cruited and parasitologically examined. The results showed that 255 of the pa-tients with 613 lesions; patients with lesion(s) induced by L. major =147 (M=63, 43%, F=84, 57%) and lesion(s) induced by L. tropica =108 (M=35, 32%, F=73, 68%). History of travel to endemic area was not always correlated with isolated Leishmania species. Conclusion: Although travel history to endemic area is an important factor to be considered for diagnosis, but parasitological confirmation is necessary initia-tion of treatment.
کلیدواژه‌های انگلیسی مقاله Cutaneous leishmaniasis,Diagnosis,Leishmania species,PCR
نویسندگان مقاله اکرم میر امین محمدی | akram mir amin mohammadi
center for research and training in skin diseases and leprosy, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

علی خامسی پور | ali khamesipour
center for research and training in skin diseases and leprosy, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

علیرضا خاتمی | alireza khatami
center for research and training in skin diseases and leprosy, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

امیر جوادی | amir javadi
department of community medicine, school of medicine, qazvin university, qazvin, iran.


منصور نصیری کاشانی | mansour nassiri kashani
center for research and training in skin diseases and leprosy, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

علیرضا فیروز | alireza firooz
center for research and training in skin diseases and leprosy, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

یحیی دولتی | yahya dowlati
center for research and training in skin diseases and leprosy, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

مسعود بهنیا | massoud behnia
department of medical parasitology and mycology, school of public health, tehran university of medical sciences, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

سید ابراهیم اسکندری | seyyed ebrahim eskandari
center for research and training in skin diseases and leprosy, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

نشانی اینترنتی http://ijpa.tums.ac.ir/index.php/ijpa/article/view/473
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