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Iranian Journal of Blood and Cancer، جلد ۱۷، شماره ۳، صفحات ۱-۴
عنوان فارسی
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عنوان انگلیسی Subcutaneous Hematoma as an Unusual Presentation of Chronic Myelogenous Leukemia following Bone Marrow Aspiration: A Case Report and Narrative Review
چکیده انگلیسی مقاله
Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm characterized by the presence of the BCR-ABL1 fusion gene, also known as the Philadelphia chromosome. Bleeding complications are uncommon in the chronic phase of CML due to preserved platelet function. However, rare cases of subcutaneous hematoma have been reported in association with factor XIII deficiency or other coagulopathies. We report the case of a 19-year-old adolescent diagnosed with CML who developed a subcutaneous hematoma after bone marrow aspiration. The patient presented with localized swelling and tenderness at the aspiration site, which was later confirmed as a hematoma on imaging. Laboratory tests revealed a preserved platelet count, but suggested a possible underlying coagulopathy. Further investigation revealed a factor XIII deficiency contributing to the unusual presentation. This case highlights the importance of considering rare bleeding disorders, such as factor XIII deficiency, in patients with CML who present with unusual bleeding manifestations. Early recognition and management of such complications are critical for optimal patient outcomes.
کلیدواژه‌های انگلیسی مقاله Chronic myeloid leukemia, Subcutaneous hematoma, Bleeding complications, Factor XIII deficiency, BCR-ABL fusion gene, Bone marrow aspiration
نویسندگان مقاله | Pourya Mashategan
Department of Pediatrics, School of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran.


| Hassan Abolghasemi
Department of Pediatrics, School of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran.


| Mohammad Kazem Emami Meibodi
Department of Orthopedics, School of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran.
نشانی اینترنتی http://ijbc.ir/browse.php?a_code=A-10-1239-2&slc_lang=en&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Pediatric Hematology & Oncology
نوع مقاله منتشر شده گزارش مورد
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