این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Journal of Research in Medical Sciences، جلد ۳۰، شماره ۵۹، صفحات ۳۰-۱
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Diagnostic methods and therapeutics strategies of Legionella infection in postbone marrow transplantation
چکیده انگلیسی مقاله Organ transplantation represents a critical therapeutic intervention for patients with end?stage organ failure or hematological malignancies, often serving as a last?resort treatment. Among these, bone marrow transplantation (BMT) is vital but complex, as it induces profound and long?lasting immunosuppression. Patients undergoing BMT are highly vulnerable to opportunistic infections due to concurrent chemotherapy, radiation, and immunosuppressive therapies. Legionella infections emerge as a significant threat, accounting for considerable morbidity and mortality in hospitalized immunocompromised individuals. These infections often progress rapidly to severe pneumonia, with high ortality rates compared to those infecting immunocompetent people. Early and accurate diagnosis remains challenging due to nonspecific clinical presentations and limitations of  onventional microbiological methods. Consequently, timely detection using advanced iagnostic tools and therapeutic intervention is necessary. This comprehensive review critically observes the epidemiology, risk factors, diagnostic methods, clinical nifestations, and treatments of Legionella in BMT recipients. It emphasizes the need for institutional prevention protocols to alleviate the exposure risks to reduce the burden of Legionella?related complications in high?risk BMT recipients.
کلیدواژه‌های انگلیسی مقاله Bacterial infections, bone marrow transplantation, legionellosis, therapeutics
نویسندگان مقاله | Sajad Ataei Azimi


| Zahra Ghorbani


| Azad Khaledi


| Kimia Safa


نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/11691
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Review Article
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات