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Medical Laboratory Journal، جلد ۱۹، شماره ۴، صفحات ۰-۰
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عنوان انگلیسی STRESSOR MARROW RESPONSE IN CASES OF NEONATAL SEPSIS-Significance of nRBCs in neonatal peripheral smears.
چکیده انگلیسی مقاله Introduction
Nucleated red blood cells (nRBC) are immature erythrocytes whose production is thought to be driven primarily by the interplay of hypoxia and erythropoietin (EPO) synthesis..It is classified as early onset neonatal sepsis(occurring with first 24 hours of life)or late onset neonatal sepsis(occurring after 48-72 hour).
We planned the study with the aim of analysing the cause for presence of nRBCs in peripheral blood of neonates sent for routine workup in the hematology Lab of Dept of Pathology,SMSR,Sharda University
Material and Method
Retrograde analysis of 27 CBC and peripheral blood smears of neonates was done  for a period of 1 month and clinical details, parameters for neonatal sepsis(NLR,PLR,LMR,IG) platelet counts and nRBC counts recorded and tabulated. For result tabulation we divided the neonatal samples into two groups 0-1 day and 2- 30 days
Results
The neonates had 17 males and 9 females. The markers for neonatal sepsis NLR ,LMR and IG were more in cases 2-30 days as compared to cases 0-1 day old. nRBCs were also raised in cases between 2-13 days old. We had 3 cases crossing nRBCs level of 200/100 WBC while 2 vases showed nRBC levels of 150/100 WBC.
Conclusion
We conclude that finding nRBCs in peripheral smear is an  important indicator of neonatal stress(sepsis/jaundice/hypoxic sepsis).
 
کلیدواژه‌های انگلیسی مقاله nRBC,Neonatal,sepsis,stressor,response
نویسندگان مقاله | Neema Tiwari
Department of Pathology, Post Graduate Institute of Child Health, Noida, India


| Richa Sharma
Department of Pathology, Santosh Medical College, Ghaziabad,India


| Prachi Saxena
Department of Pathology,School of medical science and research, Sharda University, Noida, India
نشانی اینترنتی http://mlj.goums.ac.ir/browse.php?a_code=A-10-1413-1&slc_lang=en&sid=1
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