Cell Journal، جلد ۲۷، شماره ۱، صفحات ۱-۸

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عنوان انگلیسی Applica1tion of Amniotic Membrane to Effectively Treat Chronic Cervicitis: A Case Series
چکیده انگلیسی مقاله Chronic cervicitis is a clinical syndrome characterized by persistent inflammation of the cervical epithelium. Women
with chronic cervicitis often experience symptoms such as vaginal discharge, dyspareunia, post-coital bleeding, and
fatigue. The treatment of chronic cervicitis is controversial, particularly in cases where no specific pathogenic agent be
identified. Natural wound dressings with human amniotic membranes have been successfully used in tissue healing
procedures. Thus, this approach may be a potential therapeutic option for patients suffering from chronic cervicitis. This
case series reports on five women diagnosed with chronic cervicitis. These patients had negative Pap smears, human
papillomavirus (HPV) typing tests, and colposcopic biopsies, indicating no infections or malignancies. Despite receiving
oral antibiotics, their symptoms did not improve, leading to the decision to treat them with amniotic membrane. The
cervix was assessed using a speculum, and amniotic membranes manufactured by Sinacell Company were inserted
into the affected cervical areas. The patients were instructed to avoid sexual intercourse for one week and continue
using oral antibiotics. At the follow-up, all patients significantly improved without any adverse events. Additionally,
colposcopic examinations revealed that most patients showed improvement in cervical inflammation and bleeding. The
amniotic membrane can assist women with chronic cervicitis by alleviating symptoms and enhancing the healing of
cervical ulcers without complications.
کلیدواژه‌های انگلیسی مقاله Amnion,Hemorrhage,Inflammation,ulcer,Uterine Cervicitis

نویسندگان مقاله Hanieh Najafiarab |
Preventative Gynecology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Farah Farzaneh |
Preventative Gynecology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Amirreza Keyvanfar |
Infectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Niki Talebian |
Preventative Gynecology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran


نشانی اینترنتی https://www.celljournal.org/article_726609_f3e8182474e5506acf5ab75a21fcd0d7.pdf
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