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Iranian Journal of Blood and Cancer، جلد ۱۷، شماره ۲، صفحات ۵۸-۶۹

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عنوان انگلیسی A Comprehensive Study of Prostate Cancer and Epstein-Barr Virus Infection: A Systematic Review and Meta-analysis
چکیده انگلیسی مقاله
This systematic review and meta-analysis examine the potential link between Epstein-Barr virus infection and prostate cancer development, highlighting its role in the second most common malignancy in developed countries. A complete literature search was conducted using PubMed, EMBASE, Scopus, and Web of Science to identify relevant studies published between 2002 and 2024. The study incorporated publications from various countries, peer-reviewed studies, systematic reviews, and meta-analyses as supplementary sources to identify additional relevant studies. The study analyzed data from 16 articles, involving 1,340 PC cases, assessing EBV detection based on geographical distribution, publication year, and EBV-positive cases. The odds ratio for EBV-associated PC was 26.79%, with a global prevalence of 0.38. The study indicates regional variations in EBV positivity among PC cases, suggesting a possible link between EBV infection and PC, but further research is needed to clarify its role.
کلیدواژه‌های انگلیسی مقاله Epstein-Barr virus, Prevalence, Prostate cancer, Risk factor

نویسندگان مقاله | Abolfazl Jafari-Sales
Department of Microbiology, Kaz.C., Islamic Azad University, Kazerun, Iran.


| Parisa Shiri Aghbash
Department of Virology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.


| Zahra Sadeghi-Deylamdeh
Department of Biology, Faculty of Sciences, Malayer Branch, Malayer, Iran


| Fatemeh Jahangirimehr
Department of Epidemiology and Biostatistics, School of Public Health, Isfahan University of Medical Sciences, Isfahan, Iran


| Sayed Mohsen Hosseini
Department of Epidemiology and Biostatistics, School of Public Health, Isfahan University of Medical Sciences, Isfahan, Iran


| Nooshin Amini
Department of Medical Nanotechnology, Tehran University of Medical Sciences, Tehran, Iran.


| Mehrdad Pashazadeh
Department of Medical Laboratory Sciences and Microbiology, Faculty of Medical Sciences, TaMS.C., Islamic Azad University, Tabriz, Iran.


| Hamidreza Fathi
Department of Virology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.


| Hossein Bannazadeh Baghi
Department of Virology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.



نشانی اینترنتی http://ijbc.ir/browse.php?a_code=A-10-1710-2&slc_lang=en&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Infectious Diseases
نوع مقاله منتشر شده متا آنالیز
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