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Medical Laboratory Journal، جلد ۱۹، شماره ۳، صفحات ۰-۰
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عنوان انگلیسی Clinico-epidemiology of Community and Hospital acquired Staphylococcus aureus sepsis in children. ICU needs and a change in resistance pattern.
چکیده انگلیسی مقاله Background: Staphylococcus aureus (S. aureus) is a common pathogen that causes both community and hospital-acquired infections Objectives: To identify clinico-microbial profiles of S aureus acquired in the community and in the hospital. Methods This study was conducted from January 2021 to December 2022 in Postgraduate Department of Pediatrics Children Hospital Srinagar J&K on patients aged one month to 18 years suspected of having S. aureus sepsis or disseminated disease. Results: There were 56 patients identified with S aureus septicemia (SAS) over the study period; 37(66.10%) had community acquired S aureus sepsis (CASS) and 19(33.90%) hospital acquired S aureus sepsis (HASS). 35(62.50%) affected belonged to male gender; 40(71.43%) patients belonged to rural area. Localized musculoskeletal symptoms (91.90%) were the most commonpresentation P value < 0.05. Pleuropulmonary disease and necrotizing soft tissue disease were significantly associated with patients of HASS and CASS respectively. The common disease presentation was pneumonia followed by abscess. Septic shock, respiratory failure, multi organ dysfunction, etc were the common complications seen more often in HASS. Out of 50 patients who had SAS in cultures, 48 were Methicillin resistant S aureus (MRSA) and 2 were Methicillin sensitive S aureus (MSSA). The survival rate from CASS was 94.60% and from HASS was 89.50% Conclusions: CASS and HASS affects children, is multifocal, and has high morbidity associated. The sensitivity pattern of Staphylococcus aureus in our settings as well as globally has undergone a dramatic change with rise in proportion of Methicillin resistance and needs to been addressed urgently.
 
کلیدواژه‌های انگلیسی مقاله Staphylococcus aureus sepsis, epidemiology, pediatric, antibiotic resistance.
نویسندگان مقاله | Sahar siddiqui
Senior Resident Dept of Pediatrics GMC srinagar J&K


| Mohd Suhail Lone
Associate Professor Pediatric Microbiology GMC Srinagar J&K, India.


| Umer Qureshi
Associate Professor Pediatrics Department of Pediatrics, Government Medical College, Srinagar, India.


| Rayees khanday
Child Specialist Department of Pediatrics, Government Medical College, Srinagar, India.
نشانی اینترنتی http://mlj.goums.ac.ir/browse.php?a_code=A-10-1482-1&slc_lang=en&sid=1
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