International Journal of Hematology-Oncology and Stem Cell Research، جلد ۱۹، شماره ۳، صفحات ۲۴۸-۲۶۰
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عنوان انگلیسی Evaluation of Efficacy, Safety, and Prognostic Value of Induction Chemotherapy in Patients with Acute Myeloid Leukemia: An Updated Meta-Analysis of a 5-Year Study
چکیده انگلیسی مقاله Acute Myeloid Leukemia (AML) is a type of cancer that affects the bone marrow and blood. This study aims to conduct a five-year update on induction chemotherapy's efficacy, safety, and prognostic value in patients with AML. Based on the PRISMA 2020 guidelines, a systematic search was performed on online databases for relevant studies on complete remission with incomplete hematologic response (CRi), complete remission (CR), adverse events, and overall survival. The articles obtained were observational studies that met the inclusion and exclusion criteria. The quality of the studies was assessed using the Revised Cochrane’s risk-of-bias tool. The analysis was conducted using Review Manager 5.4 and R Statistical Software 3.3. Thirteen clinical trial studies, involving 1,863 participants, were included in this survey. Based on the analysis, the CRi and CR levels, where each was obtained as a whole at 9% (random effect; 95%CI 6-13%; heterogeneity;
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نویسندگان مقاله | I Made Adi Narendranatha Komara
Department of Internal Medicine, Faculty of Medicine, Udayana University/Central General Hospital Prof. Dr. I.G.N.G Ngoerah Denpasar, Bali, Indonesia


| Ketut Suega
Medical Hemato-Oncology Division, Department of Internal Medicine, Faculty of Medicine, Udayana University/Prof. Dr. I.G.N.G. Ngoerah General Hospital, Denpasar, Bali, Indonesia


| Ni Made Renny Anggreni Rena
Medical Hemato-Oncology Division, Department of Internal Medicine, Faculty of Medicine, Udayana University/Prof. Dr. I.G.N.G. Ngoerah General Hospital, Denpasar, Bali, Indonesia


| I Wayan Losen Adnyana
Medical Hemato-Oncology Division, Department of Internal Medicine, Faculty of Medicine, Udayana University/Prof. Dr. I.G.N.G. Ngoerah General Hospital, Denpasar, Bali, Indonesia
نشانی اینترنتی https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/2294
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