Iranian Journal of Veterinary Science and Technology، جلد ۱۷، شماره ۲، صفحات ۵۱-۵۷

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عنوان انگلیسی Ergothioneeine Modulates Interleukin-6 Serum Concentration in Arabian Stallions Following a Two Thousand Meterm Race at Maximum Speed in a Hot-Dry Environment
چکیده انگلیسی مقاله This experiment was performed to determine the effect of ergothioneine’s effect on serum interleukin-6 (IL-6) concentrations after a race of 2000 m in Arabian stallions at the highest possible speed in a hot-dry environment. Twenty-four apparently healthy stallions of the Arabian breed were used. The average weight and age of the horses were 401 ± 32.11 kg and 5.7 ± 0.54 years, respectively. The experimental subjects were split assigned into three units groups of eight stallions each. Group 1 (EXEN) was neither treated with ergothioneine nor exercised. Group II (EXEC) was not treated with ergothioneine but was exercised. The third group (EXEE) was treated with ergothioneine per os at a dose rate of 0.02 mg/kg daily for one month prior to the experiment. Meteorological parameters of the study site were recorded using a dry and wet-bulb thermometer. The stallions in the EXEC and EXEE groups were made to run a race of 2000 m at the highest possible speed (60 Km/h) by trained riders. Samples of Blood samples of 10 ml were collected from all stallions before the experiment and immediately after the experiment and two hours post-experiment. The hematological parameters and concentration of IL-6 were determined in all samples.  The concentration of IL-6 was found to be higher significantly higher in the EXEE group than in others, suggesting a modulatory role of ergothioneine. Therefore, it was concluded that ergothioneine enhanced IL-6 following exercise and would be beneficial to for stallions during exercise.
کلیدواژه‌های انگلیسی مقاله Ergothioneine,Interleukin 6,Hematological Parameters,Exercise,Arabian stallions

نویسندگان مقاله Adakole Adah |
Department of Veterinary Physiology and Biochemistry, University of Ilorin, P. M. B. 1515, Ilorin, Nigeria.

Joseph Ayo |
Department of Veterinary Physiology, Ahmadu Bello University, P. M. B. 1044, Samaru- Zaria, Nigeria.

Peter Rekwot |
National Animal Production Research Institute, P. M. B. 1096, Shika-Zaria, Nigeria.

Tagang Aluwong |
Department of Veterinary Physiology, Ahmadu Bello University, P. M. B. 1044, Samaru- Zaria, Nigeria.

Adah Arimie Deborah |
Department of Veterinary Medicine, University of Ilorin, P.M.B. 1515, Ilorin, Nigeria.


نشانی اینترنتی https://ijvst.um.ac.ir/article_46715_04ad541251d0496e5af409007d362716.pdf
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