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Medical Laboratory Journal، جلد ۱۹، شماره ۱، صفحات ۰-۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Evaluation of relationship between serum zinc level and erythrocyte indices in people referring to laboratories in Gorgan city
چکیده انگلیسی مقاله background:
Bivalent minerals have an important role as cofactors which play vital roles in various metabolic pathways in the body. Zinc (Zn) has catalytic, structural, and regulatory roles. Severe Zn deficiency may cause the abnormal synthesis of nucleic acids, and proteins, impaired cellular growth, excessive cell death, and excess lipid peroxidation of the cellular membrane that is associated with shortening the RBC lifespan.
Purpose:
The aim of this study was to examine the associations between Zn status and the erythrocyte indices.
Methods and materials:
A number of 563 individuals (72.8% female) were included in this study. The level of serum Zn was measured by photometric method and blood index values were measured by using a cell counter.
Results:
The average serum Zn level is 102.8± 17.6 mg/dl. Serum Zn level is directly related with RBC (R=0.119, PV=0.005) and MCHC (R=0.086, PV=0.041) but it is inversely related with MCV (R=-0.097, PV=0.021). These results also determined that serum Zn level, as well as the levels of RBC, Hb, HCT, and MCHC, were significantly higher in men (Sig<0.01) but the level of MCV among women was higher (Sig<0.01). Moreover, in individuals with <30   serum Zn level, MCHC (Sig<0.01), and RBC (Sig<0.05) were higher whereas Hb (Sig<0.05), HCT, MCV, and MCH (Sig<0.01) were higher at >30.
Conclusion:
According to the positive relationship between Zn level and RBC, Zn deficiency affects the number of RBCs.
 
کلیدواژه‌های انگلیسی مقاله Zinc, Erythrocyte, MCV, MCH, MCHC
نویسندگان مقاله | Zahra Eslami
Metabolic Disorders Research Center, Golestan University of Medical Sciences, Gorgan, Golestan province, Iran


| Shayan Marhamaty
student of clincal biochemistry, Hamadan University of Medical Sciences, Hamadan, Hamadan province, Iran


| Mehdi Jafari
Metabolic Disorders Research Center, Golestan University of Medical Sciences, Gorgan, Golestan province, Iran


| Mohadese Khorasani
Ph.D. student of analytical chemistryLaboratory Assistant at Golestan University of Medical Sciences


| Mehdi Sheikh Arabi
Medical Cellular and Molecular Research Center, Golestan University of Medical Sciences, Gorgan, Iran


| Hamidreza Joshaghani
Laboratory Sciences Research Center, Golestan University of Medical Sciences, Gorgan, Iran
نشانی اینترنتی http://mlj.goums.ac.ir/browse.php?a_code=A-10-638-1&slc_lang=en&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده خون شناسی آزمایشگاهی و بانک خون
نوع مقاله منتشر شده تحقیقی
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