| چکیده انگلیسی مقاله |
Mycosis fungoides (MF) is the most common subtype of cutaneous T-cell lymphoma (CTCL) and is characterized by a heterogeneous clinical course and variant stage involvement. Indolent disease is usually observed in its early stages. However, the treatment options for patients with advanced MF are limited and have poor outcomes. Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a potential curative treatment for refractory cases. Here, we describe the case of a 34-year-old man who was diagnosed with MF at an advanced stage. Eight months before allo-HSCT, the patient received six courses of polychemotherapy based on cyclophosphamide, doxorubicin, vincristine, and prednisolone, which were administered every three weeks. A partial response was obtained.
He underwent allo-HSCT after a myeloablative conditioning regimen and remained in complete remission (CR) for 26 months posttransplantation. Our findings confirm that allo-HSCT can be a curative option for refractory MF. |
| نویسندگان مقاله |
| Mekni Sabrine
Faculty of Medicine, University of Tunis El Manar, National Center of Stem cell Transplantation, Tunis, Tunisia
| Ben Hana
Faculty of Medicine, University of Tunis El Manar, National Center of Stem cell Transplantation, Tunis, Tunisia
| Noureddine Litaiem
Faculty of Medicine, University of Tunis El Manar, National Center of Stem cell Transplantation, Tunis, Tunisia
| Kanoun Yosra
Faculty of Medicine, University of Tunis El Manar, National Center of Stem cell Transplantation, Tunis, Tunisia
| Torjemane Lamia
Faculty of Medicine, University of Tunis El Manar, National Center of Stem cell Transplantation, Tunis, Tunisia
| Belloumi Dorra
Faculty of Medicine, University of Tunis El Manar, National Center of Stem cell Transplantation, Tunis, Tunisia
| Ben Insaf
Faculty of Medicine, University of Tunis El Manar, National Center of Stem cell Transplantation, Tunis, Tunisia
| Ouerghi Rihab
Faculty of Medicine, University of Tunis El Manar, National Center of Stem cell Transplantation, Tunis, Tunisia
| Turki Ines
Faculty of Medicine, University of Tunis El Manar, National Center of Stem cell Transplantation, Tunis, Tunisia
| Chaabane Anna
Faculty of Medicine, University of Tunis El Manar, National Center of Stem cell Transplantation, Tunis, Tunisia
| Ben Tarek
Faculty of Medicine, University of Tunis El Manar, National Center of Stem cell Transplantation, Tunis, Tunisia
| Ben Nour
Faculty of Medicine, University of Tunis El Manar, National Center of Stem cell Transplantation, Tunis, Tunisia
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