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Veterinary Research Forum، جلد ۱۶، شماره ۴، صفحات ۲۰۳-۲۰۸
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Determination of the effect of Tarantula cubensis alcoholic extract on cadmium embryotoxicity |
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| چکیده انگلیسی مقاله |
Tarantula cubensis alcoholic extract (TCAE) is a homeopathic product used in the veterinary field. This study aimed to determine the effects of TCAE on cadmium (Cd) toxicity in the embryo. The study used 220 fertile, incubated chicken eggs divided into 11 equal groups on the 7th day of incubation. The groups comprised untreated and physiological saline control groups, a group with TCAE alone, four groups with varying doses of Cd alone and four groups with the same doses of Cd plus TCAE. At the end of the incubation period, the eggs were opened, kidney and liver tissue samples were taken for histopathology and the number of dead and living embryos were recorded. In the prsent study, the median lethal dose of Cd was determined to be 0.029 mg per egg and the median lethal dose of Cd plus TCAE was determined to be 0.020 mg per egg. The histopathological examinations determined that kidney and liver damage were increased when TCAE and Cd were administered together, that was higher than when Cd was given alone. Thus, TCAE, which had no toxic effect on the embryo when used alone, might increase the embryotoxic activity of Cd. However, more detailed studies are needed. |
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| کلیدواژه‌های انگلیسی مقاله |
Tarantula cubensis alcoholic extract,Cadmium,Embryotoxic,in ovo methods |
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| نویسندگان مقاله |
Rahmi Canbar |
Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Necmettin Erbakan University, Konya, Türkiye
Gokhan Akcakavak |
Department of Pathology, Faculty of Veterinary Medicine, Aksaray University, Aksaray, Türkiye
Muhittin Uslu |
Department of Laboratory and Veterinary Health, Sefaatli Vocational College, Yozgat Bozok University, Yozgat, Türkiye
Mustafa Sedat Arslan |
Prof. Dr. Humeyra Ozgen Research and Application Farm, Faculty of Veterinary Medicine, Selcuk University, Konya, Türkiye
Harun Kizilay |
Department of Pharmacology, Faculty of Pharmacy, Selcuk University, Konya, Türkiye
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| نشانی اینترنتی |
https://vrf.iranjournals.ir/article_722223_b34b5cfedf3e43f3768b63965e51101f.pdf |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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| نوع مقاله منتشر شده |
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