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Journal of Medicinal Plants and By-products، جلد ۱۴، شماره ۲، صفحات ۱۲۱-۱۲۶

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عنوان انگلیسی Investigating the Effect of Taraxacum officinale Extract on Wistar Rats’ Infertility Induced by Cadmium Chloride
چکیده انگلیسی مقاله This study was conducted to investigate the efficacy of Taraxacum officinale F.H.Wigg. extract on the infertility of male rats. In this research, we investigated the impacts of T. officinale extract on the infertile cadmium chloride-induced Wistar rats. T. officinale extract was fed to mice daily for 28 days with the help of a gavage needle. Then, all 40 rats were anesthetized with ether and dissected, then epididymis were examined morphologically. Also, we analyzed their right tests for cell line counts and H/E staining and their left testicles were analyzed to evaluate superoxide dismutase (SOD) and malondialdehyde (MDA) enzymes. Our analysis of three sperm quality parameters showed a significant increase in viability, motility and the number of sperm cells in infertile groups treated with 100, 200, and 400 mg/kg T. officinale extract. Our SOD analysis revealed T. officinale extract caused to produce more enzymes in the healthy experimental groups, even compared to the healthy control group. Also, our analysis indicated that increasing the dosage of the T. officinale extract resulted in increasing enzyme production in infertile groups. MDA analyses showed that the healthy experimental groups produced a lower amount of MDA enzyme, which is almost the same level as the healthy control group. Also, due to the usage of T. officinale extract, the level of lipid peroxidation and MDA significantly decreased. In the current study, T. officinale extract can have significant positive impacts on the viability, motility, number of sperms in oxidative stress conditions.
کلیدواژه‌های انگلیسی مقاله Taraxacum officinale,male fertility,oxidative stress,spermatogenesis

نویسندگان مقاله Soraya Moradi |
Faculty of veterinary medicine, Science and research branch, Islamic azad university, Tehran, Iran

Sajed Khaledi |
Department of Anatomical Sciences, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran

Mehdi Mehdinezhad Roshan |
Department of Biology and Anatomical Sciences, School of medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Mohammadamin Eslampour |
Department of clinical sciences, Faculty of veterinary medicine, Science and research branch, Islamic azad university, Tehran, Iran

Hanie Khodadadi |
Faculty of veterinary medicine, Science and research branch, Islamic azad university, Tehran, Iran

Pejman Mortazavi |
Department of pathology, Faculty of veterinary medicine, Science and research branch, Islamic Azad University, Tehran, Iran


نشانی اینترنتی https://jmpb.areeo.ac.ir/article_131061_ba9c5b27c66d28d8350698a93f18362c.pdf
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