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Caspian Journal of Enviromental Sciences، جلد ۲۲، شماره ۴، صفحات ۹۹۳-۹۹۸
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عنوان انگلیسی Correction of liver changes caused by alcohol rates with probiotics
چکیده انگلیسی مقاله There is evidence of the beneficial effects of probiotics in fatty liver cases. This study aims to evaluate the effects of probiotic intake on several metabolic factors in people with fatty liver. Eighty patients with fatty liver with a body mass index above 25 were divided into three groups: the control group, the alcohol group, and the probiotic group. After 45 days, fasting blood samples, physical changes, and dietary intakes were measured over the experiment. Statistical analysis was performed with SPSS software, and variance analysis was done. Significant reduction in weight (4%) and BMI (5%) was observed (p-value less than 0.001). The percent changes in weight and BMI were at a rate of 4.8% compared to the control group. The waist circumference in both groups showed a significant difference after the intervention, with the probiotic group decreasing by 8% compared to the control group. The findings showed that probiotic treatment was beneficial in reducing the severity of liver damage, most likely through increasing beneficial bacteria and reducing inflammatory responses and oxidative stress, and led to weight loss and BMI.
کلیدواژه‌های انگلیسی مقاله Fatty liver, Adipokines, Alcohol, probiotic
نویسندگان مقاله Zhadyra Orynbayeva |
Abai Kazakh National Pedagogical University, Faculty of Natural Sciences and Geography, Almaty, Kazakhstan

Zina Tungushbayeva |
Abai Kazakh National Pedagogical University, Faculty of Natural Sciences and Geography, Almaty, Kazakhstan

Kundyz Nurlybayeva |
Karaganda Buketov University, Karaganda, Kazakhstan

Fatima Abikenova |
Department of Physiology, NP JSC “Karaganda Medical University”, Karaganda, Kazakhstan

Urszula Jankiewicz |
Warsaw University of Life Sciences, Biochemistry and Microbiology Department, Institute of Biology. Warsaw, Poland

Ainur Seilkhan |
Abai Kazakh National Pedagogical University, Faculty of Natural Sciences and Geography, Almaty, Kazakhstan

Laura Koibasova |
Institute of Genetics and Physiology, MS MHES RK, Almaty, Kazakhstan

Usen Kurmanbay |
Department of Chemistry and Biology, Faculty of Pedagogical and Natural Sciences, Zh. Tashenev university, Shymkent, Kazakhstan

نشانی اینترنتی https://cjes.guilan.ac.ir/article_8123_a4309cdcb02ddfdf05b34cfbf81aa163.pdf
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