| چکیده انگلیسی مقاله |
Background: Helicobacter pylori (H.pylori) is a common bacterial infection, with considerably high morbidity and mortality worldwide. This bacterium represents a key factor in the etiology of various chronic infections ranging from gastritis, peptic ulcer disease to gastric cancer; but the prevalence has large variations in different communities. The aim of this study was to estimate the prevalence H. pylori infection in a nationally representative sample of Iranian adolescents.Materials and Methods: In this cross-sectional study, serum samples of 882 Iranian adolescents, aged 10-18 years, were examined for seroprevalence of H.pylori. They were randomly selected from the samples obtained in the third survey of a national surveillance program (the CASPIAN III study). Seroprevalence of H. pylori was examined by detection of H. pylori immunoglobulinA (IgA), immunoglobulinG (IgG) and immunoglobulinM (IgM) in sera by using Enzyme Linked Immunosorbant Assay (ELISA).Results: The study participants had a mean age of 14.82 + 2.77 years. Overall, 51.7% of students were boys and 61.52% were urban residents. The H. pylori IGM and IGA seropositivity had no significant association with demographic characteristics (p>0.05). The H. pylori IgG seropositivity were significantly different in boys and girls (69.7%, 95% confidence interval [CI] = 66.7-72.7 vs. 76.3%, 95%CI= 73.5-79. 1, respectively, P=0.03).Conclusion: The seroprevalence of H. pylori IgG in Iranian adolescents is high, and girls had greater risk of H. pylori IgG seropositivity compared to boys. Preventive strategies and health education are recommended to reduce the prevalence of this infection in Iranian adolescent. |
| نویسندگان مقاله |
عنایت الله کلانتر | enayatollah kalantar
dietary supplements and probiotics research center, alborz university of medical sciences, karaj, iran.
محمد جواد غروی | mohammad javad gharavi
deputy of research affairs, alborz university of medical sciences, karaj, iran.
مژگان عشاقی | mojgan oshaghi
department of microbiology and immunology, school of paramedical sciences, iran university of medical sciences, tehran, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)
بهناز قره گزلو | behnaz gharegozlou
department of microbiology and immunology, school of paramedical sciences, iran university of medical sciences, tehran, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)
سارا محمدی | sara mohammadi
deputy of research affairs, alborz university of medical sciences, karaj, iran.
رامین حشمت | ramin heshmat
epidemiology department, chronic diseases research center, endocrinology and metabolism population sciences institute, tehran university of medical sciences, tehran, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)
شروین غفاری حسینی | shervin ghaffari hoseini
infectious diseases and tropical medicine research center, isfahan university of medical sciences, isfahan, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)
محمد اسماعیل مطلق | mohammad esmaeil motlagh
department of pediatrics, ahvaz jundishapur university of medical sciences, ahvaz, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی جندی شاپور اهواز (Ahvaz jundishapur university of medical sciences)
مصطفی قربانی | mostafa qorbani
non-communicable of disease research center, alborz university of medical sciences, karaj, iran amp;amp; chronic diseases research center, endocrinology and metabolism population sciences institute, tehran university of medical sciences, tehran, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)
رویا کلیشادی | roya kelishadi
department of pediatrics, child growth and development research center, research institute for primordial prevention of non-communicable disease, isfahan university of medical sciences, isfahan, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)
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