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Iranian Endodontic Journal، جلد ۱۲، شماره ۲، صفحات ۱۵۷-۱۶۱

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عنوان انگلیسی Subcutaneous Reaction of Rat Tissues to Nanosilver Coated Gutta-Percha
چکیده انگلیسی مقاله Introduction: Gutta-percha (GP), is a neutral and non-toxic material. The aim of this animal study was to compare the biocompatibility of nanosilver coated GP (NS-GP) with conventional GP in subcutaneous tissues in a rat model. Methods and Materials: Conventional GP and NS-GP were subcutaneously implanted in the backs of 20 male Wistar rats ( n =10). A control animal was assigned for each trial period. Ten animals were sacrificed after 7 and 30 days and light microscopic evaluation of tissue reaction to NS-GP ( n =20) and conventional GP ( n =20) was accomplished. The Mann-Whitney U, Wilcoxon Signed Ranks, Fisher Exact, and McNemar tests were used for statistical analysis of the data. Results: After 7 days, inflammation was moderate and mild for NS-GP and conventional GP, respectively ( P < 0.001). After 30 days, no inflammation was discernible in conventional GP. However, mild inflammation was reported for NS-GP ( P < 0.001). Regarding inflammatory cell type, there was a significant difference between two experimental groups at both times ( P < 0.001). Conclusion: Inflammation decreased over time in both groups. Fibrous connective tissue, a representative of healing and control of inflammatory process, surrounded both test materials. NS-GP was biocompatible and might be a reasonable endodontic obturation material.
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نویسندگان مقاله محمد علی مزینی | mohammad ali mozayeni


امید دیانت | omid dianat


شاهین تحویلداری | shahin tahvildari


مریم مزینی | maryam mozayani


پیام paymanpour | payam paymanpour



نشانی اینترنتی http://journals.sbmu.ac.ir/iej/article/view/11439
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/109/article-109-326832.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Article
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