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Medical Laboratory Journal، جلد ۱۰، شماره ۳، صفحات ۰-۰
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Evaluation prevalence of Rh system major antigens (D, C, c, E, e) and their phenotypes in blood donors of Golestan province, Iran |
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| چکیده انگلیسی مقاله |
Background and Objectives:
Blood donors are examined for the antigens of the ABO and Rh systems. The aim of this study was to determine the frequency of Rh system antigens (D, C, c, E, e) and its phenotype in the blood donors with a view to, Identify the blood group phenotypes of the donors in any population is important to improve health care services and to better serve patients.
Methods:
A descriptive study was carried on 575 healthy donors (Turkmen and Fars) referred to blood transfusion centers in Golestan province. From each sample, a cell suspension (3-5%) was prepared in normal saline and exposed to Rh system antiserums using haemagglutination technique. Finally, Rh phenotype was determined based on the most common genotype.
Results:
For the Rh system, the antigen frequencies of D, C, c, E, and e are respectively, 87.76%, 73.6%, 72.1%, 30.83%, and 93.59%.The most common phenotype in donors (Turkmen and Far) was R1R1 , R1r and rr respectively, and the lowest was R2Rz, ryry. The phenotype r'r' and ryry in Turkmen donors and phenotype r''r' in Fars donors were not detected.
Conclusion:
Identifying the prevalence of blood group antigens from donors in each region is important in organizing negative antigen blood units, preparing compatible blood for multitransfused and preventing the development of alloantibodies in these patients.
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| کلیدواژه‌های انگلیسی مقاله |
Phenotype, Blood Donors, Rh blood group antigens, Iran |
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| نویسندگان مقاله |
| sadegh baniaghil
Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Gorgan, Iran
| fardin balochi
Immunology, Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran
| alireza ahmadi
Medical laboratory Science, Faculty of Paramedicine, Golestan University of Medical Sciences, Golsan, Iran
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| نشانی اینترنتی |
http://mlj.goums.ac.ir/browse.php?a_code=A-10-1361-1&slc_lang=en&sid=1 |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
ایمنی شناسی |
| نوع مقاله منتشر شده |
Research Article |
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