International Journal of Pediatrics، جلد ۵، شماره ۱، صفحات ۴۱۱۷-۴۱۲۴

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عنوان انگلیسی Hypertonic 3% Saline in Comparison with 0.9% (Normal) Saline in Treatment of Acute Bronchiolitis
چکیده انگلیسی مقاله BackgroundBronchiolitis is the commonest cause of lower respiratory tract infection in infant. Respiratory syncytial virus is the commonest cause of bronchiolitis. This study aimed to assess the efficacy of nebulized 3% hypertonic saline and salbutamol in the treatment of acute bronchiolitis in comparison with nebulized 0.9% saline and salbutamol.Materials and MethodsA prospective case second multicenter study was done at two pediatric tertiary centers at the period from 1st of December 2014 to 31 of March 2015. A total of 100 previously well infant and children of age 1-24 months with clinical diagnoses of bronchiolitis who were admitted to the hospital were included. They were divided into two groups, the study group received 4 ml of nebulized hypertonic 3% saline (for 14 days), and second group received 4 ml of nebulized normal 0.9% saline (for 14 days), each co-administer with 0.5 ml salbutamol.ResultsAll patients with acute bronchiolitis having similar baseline characteristic, mean age 4.9 + Standard deviation (SD) months, male gender constitutes 68% of the patients and the majority (67%) of the cases were below 6 months. The mean of clinical severity score at admission was 6.4 for normal saline (NS) group and 6.6 for hypertonic 3% saline (HS) group. The mean length of hospital stay of normal saline group = 4.3 + Standard deviation (SD) day and for hypertonic saline group was = 4.7 + Standard deviation (SD) day.ConclusionWe didn’t find any advantage of hypertonic 3% saline over 0.9% normal saline in terms of length of hospital stay and clinical severity score.
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نویسندگان مقاله بینتی کریم جاسم محمد al bahadily | abdul karem jasem mohammed al bahadily
professor and dean, ficps, college of medicine, maysan university, maysan, iraq.


areege بینتی عباس محمد al عمرانی | areege abdul abass mohammed al omrani
assistant professor, cabp, pediatric department, college of medicine, al-nahrain university, baghdad, iraq.


اسعد a atiya | asaad a atiya
board student doctor, pediatric department, college of medicine, al-nahrain university, baghdad, iraq.



نشانی اینترنتی http://ijp.mums.ac.ir/article_8105.html
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