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Avicenna Journal of Phytomedicine، جلد ۷، شماره ۱، صفحات ۹۳-۹۸

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عنوان انگلیسی Antinociceptive action of Vanillosmopsis arborea in male mice
چکیده انگلیسی مقاله Objective: Vanillosmopsis arborea Baker (Asteraceae) has high economic value from Chapada to Araripe and its bark essential oil is a potential source of alpha-bisabolol. The present study aimed to elucidate the antinociceptive and antipruritic properties of the essential oil of V. arborea Baker (EOVA) in mice. Materials and Methods: The antinociceptive activity was assessed using the capsaicin, glutamate, hot plate and cold allodynia tests. The antipuritic effects were also verified based on histamine-induced scratching behavior. Results: EOVA reduced the paw licking induced by capsaicin, but not that induced by glutamate. The essential oil increased the latency time in the hot plate, attenuated the cold allodynia induced by acetone and inhibited histamine-induced scratching behavior. Conclusion: The experimental data demonstrated that EOVA showed central and peripheral antinociceptive activity and antipruritic effect.
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نویسندگان مقاله لورا inocencio لیتی | laura inocencio leite
department of biology at the federal university of cariri, brejo santo – ce, brazil


gerlânia de اولیورا لیتی | gerlânia de oliveira leite
department of pharmacology, university of santa maria, santa maria- rs, brazil


برونو اندرسن fernandes سیلوا | bruno anderson fernandes silva
department of chemical biological at the regional university of cariri, crato – ce, brazil


severino denício gonçalves sousa | severino denício gonçalves sousa
department of chemical biological at the regional university of cariri, crato – ce, brazil


thales coutinho | thales coutinho
department of chemical biological at the regional university of cariri, crato – ce, brazil


renata sampaio | renata sampaio
department of chemical biological at the regional university of cariri, crato – ce, brazil


irwin menezes | irwin menezes
department of chemical biological at the regional university of cariri, crato – ce, brazil


جوز galberto martins costa | josé galberto martins costa
department of chemical biological at the regional university of cariri, crato – ce, brazil


adriana campos | adriana campos
department of fharmacology at the university of fortaleza, fortaleza – ce, brazil



نشانی اینترنتی http://ajp.mums.ac.ir/article_6956.html
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/232/article-232-313973.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Original Research Article
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