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Journal of Nanostructures، جلد ۱۳، شماره ۳، صفحات ۶۱۷-۶۲۵
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عنوان انگلیسی Green Synthesis of Silver Nanoparticles Using Trachyspermum Ammi Fruit Extract: Characterization and Antibacterial Activity
چکیده انگلیسی مقاله In recent years, bimetallic nanoparticles have gained prominence in medical science due to their biomedical properties. This research aimed to develop an eco-friendly, simple and facile process to synthesizing green silver nanoparticles (AgNPs) using Trachyspermum ammi fruit extract. The synthesized silver nanoparticles were characterized using FT-IR, UV-Vis spectroscopy, XRD, DLS, and TEM. The minimum inhibitory concentration (MIC) values of the synthesized AgNPs and T. ammi extract for five standard bacteria strains were determined by the broth microdilution method. The obtained AgNPs exhibited Surface Plasmon Resonance centered at approximately 415 nm, with an average particle size calculated to be 50 nm. The mean particle size and surface charge of biosynthesized AgNPs using T. ammi extract investigated by DLS and zeta potential were 26.78±1.24 nm and -13.96 mV, respectively. Furthermore, green synthesized AgNPs showed high and efficient antibacterial activity against E. coli ATCC 25922, P. aeruginosa ATCC 27853, K. pneumonia ATCC 9997, S. aureus ATCC 25923, and E. faecalis ATCC 29212 with MIC values of 19, 19.5, 75, 150, and 39 µg/ml, respectively. Notably, the antibacterial results illustrated that green synthesized AgNPs possess significantly higher antibacterial potency than chemically produced silver nanoparticles. Our findings highlight the effective and efficient synthesis of silver nanoparticles by T. ammi fruit extract and its significant antibacterial activities.   
کلیدواژه‌های انگلیسی مقاله Antibacterial activity Green synthesis, Minimum inhibitory concentration, Silver nanoparticles, Trachyspermum ammi
نویسندگان مقاله Mohammad Yahya Hanafi-Bojd |
Department of Pharmaceutics and Pharmaceutical nanotechnology, School of Pharmacy, Birjand University of Medical Sciences, Birjand, Iran

Sima Hasheminezhad |
Student Research Committee, Birjand University of Medical Sciences, Birjand, Iran

Effat Alemzadeh |
Infectious Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran

Sobhan Mortazavi Derazkola |
Medical Toxicology and Drug Abuse Research Center (MTDRC), Birjand University of Medical Sciences, Birjand, Iran

Masoud Yousefi |
Department of Medical Microbiology, School of Medicine, Infectious Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran

نشانی اینترنتی https://jns.kashanu.ac.ir/article_114288_9a6e27778dce171b3e32851af06497d8.pdf
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