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Journal of Research in Medical Sciences، جلد ۲۸، شماره ۴۱، صفحات ۲۹-۱
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عنوان انگلیسی Seroepidemiology of Toxoplasma gondii in diabetic patients type 2 by enzyme linked immunosorbent assay method in Zabol City 2017–2018
چکیده انگلیسی مقاله Background: Type 2 diabetes mellitus (T2DM) is prone to opportunistic infections, including toxoplasmosis, due to an immunodeficiency system. This study aimed to evaluate the serum of people with T2DM to determine the titer of anti?toxoplasma antibodies in patients and compare it with the control group. Materials and Methods: 720 blood samples have been carried out between October and the end of January 2017 in Sistan, and Baluchestan provinces in southeastern Iran, of these, 360 samples were related to healthy individuals (control), and 360 samples were related to T2DM individuals. The immunoglobulin (Ig) M and IgG enzyme?linked immunosorbent assay methods have been used to detect toxoplasmosis. The data were analyzed using SPSS?19,Chi?square, and Fisher’s exact test to compare statistical parameters. Results: In this cross?sectional study, out of 360 samples of T2DMby ELISA method, 60% samples in diabetic patients and 48.1% in control group were IgG positive (P < 0.05). Nearly 2.5% samples in diabetic patients and 0.3% in control group were IgM positive (P < 0.05). Conclusion: Anti?toxoplasma antibodies including IgG and IgM were higher in diabetic patient in comparison to control group.
کلیدواژه‌های انگلیسی مقاله Antibody, diabetes, enzyme?linked immunosorbent assay, Toxoplasma gondii
نویسندگان مقاله | Mansour Dabirzadeh


| Mojtaba Sargazi


| Somayeh Bagher


نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/11514
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Short Communication
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