این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Journal of Sciences Islamic Republic of Iran، جلد ۲۱، شماره ۲، صفحات ۰-۰
عنوان فارسی Synthesis of New Pyridine Based ۴-Thiazolidinones Incorporated Benzothiazoles and Evaluation of Their Antimicrobial Activity
چکیده فارسی مقاله Substituted Schiff bases (hydrazones) 5a-j have been prepared from the starting material 2-chloro pyridine-3-carboxylic acid 1 by a sequence of reactions like reaction with 2-amino-6-nitro benzothiazole (Ullamann condensation), thionyl chloride, hydrazine hydrate and different aromatic aldehydes. On cyclocondensation of 5a-j with thioglycolic acid in dry 1,4-dioxane furnished desired compounds 4-thiazolidinones 6a-j. The structures of all the synthesized compounds have been assigned on the basis of IR, 1H NMR, 13C NMR spectral data and elemental analyses. All the newly synthesized compounds were tested for their in vitro antimicrobial activity against several microbes. Some of the compounds showed significant antibacterial as well as antifungal activity.
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Synthesis of New Pyridine Based 4-Thiazolidinones Incorporated Benzothiazoles and Evaluation of Their Antimicrobial Activity
چکیده انگلیسی مقاله Substituted Schiff bases (hydrazones) 5a-j have been prepared from the starting material 2-chloro pyridine-3-carboxylic acid 1 by a sequence of reactions like reaction with 2-amino-6-nitro benzothiazole (Ullamann condensation), thionyl chloride, hydrazine hydrate and different aromatic aldehydes. On cyclocondensation of 5a-j with thioglycolic acid in dry 1,4-dioxane furnished desired compounds 4-thiazolidinones 6a-j. The structures of all the synthesized compounds have been assigned on the basis of IR, 1H NMR, 13C NMR spectral data and elemental analyses. All the newly synthesized compounds were tested for their in vitro antimicrobial activity against several microbes. Some of the compounds showed significant antibacterial as well as antifungal activity.
کلیدواژه‌های انگلیسی مقاله Antimicrobial activity, Schiff bases (hydrazones)
نویسندگان مقاله N.B Patel |


نشانی اینترنتی https://jsciences.ut.ac.ir/article_20877_bd6ee4020dcfe2fa7ab56d50db5294a9.pdf
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات