| چکیده انگلیسی مقاله |
Background: Antimicrobial stewardship program is a comprehensive, longitudinal program designed to improve and measure the appropriateness of antimicrobial use while increasing patients' safety, decreasing cost of patients' care, and combating emerging antimicrobial resistance. Antimicrobial resistance, specially emerging multidrug-resistance and extremely drugresistance gram negative bacteria, is an important concern in the modern world. This is particularly problematic since antimicrobials in production pipelines are not meeting the demand for the emerging resistance micro-organisms; in another word "we are running out of options". Indiscriminate use of antimicrobial may increase the risk for resistance, and drug toxicity. The aim of this study is to implement an evidence-based antimicrobial stewardship program in a tertiary referral hospital. This study will assure consistency of the stewardship program and measure outcomes to further assess the effectiveness of this program. Materials and Methods: After establishment of antimicrobial stewardship committee and endorsement of policies the program will be conducted in all hospital medical wards. In an observational study, all patients receiving antimicrobials included in the program will be closely monitored for primary and secondary outcomes. Hospital's antimicrobial resistance patterns are monitored periodically to assess improvement. The quality indicators will be assessed to ensure proper execution of the program over time. Results: As a study protocol, there are no results available to be reported at this time. Conclusion: We are expecting to observe significant reduction in cost of antibiotic use shortly after program execution. By more appropriate utilization of antibiotics patients' safety will be increased. Furthermore, we are expecting to detect improvement in antimicrobial resistance patterns. |
| نویسندگان مقاله |
Hamidreza Jamaati |
Chronic Respiratory Diseases Research Center,
National Research Institute of Tuberculosis and Lung
Diseases (NRITLD), Shahid Beheshti University of
Medical Sciences, Tehran, Iran,
Farzaneh Dastan |
Chronic Respiratory Diseases Research Center,
National Research Institute of Tuberculosis and Lung
Diseases (NRITLD), Shahid Beheshti University of
Medical Sciences, Tehran, Iran,
Zahra Mirshafiei Langari |
Department of Pharmaceutical Care, NRITLD, Shahid
Beheshti University of Medical Sciences, Tehran, Iran,
Roodabeh Haghgoo |
Department of Pharmaceutical Care, NRITLD, Shahid
Beheshti University of Medical Sciences, Tehran, Iran,
Raha Eskandari |
Department of Pharmaceutical Care, NRITLD, Shahid
Beheshti University of Medical Sciences, Tehran, Iran
Majid Marjani |
Clinical Tuberculosis and Epidemiology Research
Center, NIRTLD, Shahid Beheshti University of Medical
Sciences, Tehran, Iran,
Afshin Moniri |
Clinical Tuberculosis and Epidemiology Research
Center, NIRTLD, Shahid Beheshti University of Medical
Sciences, Tehran, Iran
Seyed Mohammadreza Hashemian |
Clinical Tuberculosis and Epidemiology Research
Center, NIRTLD, Shahid Beheshti University of Medical
Sciences, Tehran, Iran
Behrooz Farzanegan |
Tracheal Diseases Research
Center, NIRTLD, Shahid Beheshti University of Medical
Sciences, Tehran, Iran
Atefeh Abedini |
Clinical Tuberculosis and Epidemiology Research
Center, NIRTLD, Shahid Beheshti University of Medical
Sciences, Tehran, Iran.
Payam Tabarsi |
Clinical Tuberculosis and Epidemiology Research
Center, NIRTLD, Shahid Beheshti University of Medical
Sciences, Tehran, Iran.
Ali Akbar Velayati |
Clinical Tuberculosis and Epidemiology Research
Center, NIRTLD, Shahid Beheshti University of Medical
Sciences, Tehran, Iran,
|