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Tanaffos، جلد ۱۸، شماره ۱، صفحات ۷۹-۸۳
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Effect of Intrapleural Meperidine on Post-Operative Pain after Open Cholecystectomy |
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| چکیده انگلیسی مقاله |
Background: Post-operative pain after open cholecystectomy can result in increased oxygen consumption, atelectasis, pneumonia, decreased vital capacity, and increased morbidity and mortality. The aim of this study was to compare the analgesic effects of intrapleural meperidine and intravenous morphine in controlling post-cholecystectomy pain. Materials and Methods: In a double-blinded randomized clinical trial, 72 patients who were candidate for elective open cholecystectomy, were divided randomly into two groups based on accidental randomized numbers. Anesthesia technique was precisely the same for all patients. At the end of surgery, 50 mg of meperidine (diluted in 20 cc normal saline) was injected intrapleurally for meperidine group patients; whereas, 0.1 mg/kg intravenous morphine was injected intravenously in control group. Onset of pain and total dose of rescue analgesic were measured. Results: In order to obtain a Numerical Rating Scale (NRS) <3, the difference in morphine consumption up to 12 hours in two groups (4.4 ±1.7 mg in meperidine group & 5±2 mg in control group) was not statistically different. However, the first request for analgesia in meperidine group was delayed significantly longer than the control group (146.6 ±6.8 minutes in meperidine group & 40 ±1.8 minutes in control group). Conclusion: A single injection of intrapleural meperidine can delay the first request for analgesia in open cholecystectomy compared to intravenous morphine. |
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| کلیدواژه‌های انگلیسی مقاله |
Cholecystectomy,Pain,Intrapleural,Meperidine |
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| نویسندگان مقاله |
Kamran Mottaghi |
Anesthesiology Research Center, Department of
Anesthesiology, Shahid Beheshti University of Medical
Sciences, Tehran, Iran
Farhad Safari |
Anesthesiology Research Center, Department of
Anesthesiology, Shahid Beheshti University of Medical
Sciences, Tehran, Iran
Parisa Sezari |
Anesthesiology Research Center, Department of
Anesthesiology, Shahid Beheshti University of Medical
Sciences, Tehran, Iran
Alireza Salimi |
Anesthesiology Research Center, Department of
Anesthesiology, Shahid Beheshti University of Medical
Sciences, Tehran, Iran
Masoud Nashibi |
Anesthesiology Research Center, Department of
Anesthesiology, Shahid Beheshti University of Medical
Sciences, Tehran, Iran
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| نشانی اینترنتی |
https://www.tanaffosjournal.ir/article_242162_9a307cb01ef3e9e36c4cbef96f3ae1df.pdf |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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| نوع مقاله منتشر شده |
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