این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Tanaffos، جلد ۲۱، شماره ۲، صفحات ۲۵۳-۲۵۶
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Reversible Acute Lung Injury due to Bleomycin
چکیده انگلیسی مقاله Bleomycin is a unique antibiotic agent with cytotoxic activity and is used successfully in various malignant diseases, such as Hodgkin lymphoma and germ cell tumors. Drug-induced lung injury (DILI) is one of the major limitations of bleomycin administration in particular clinical settings. The incidence varies among patients and depends on a variety of risk factors, such as cumulative drug dose, underlying malignant disease, and concurrent radiation. The clinical presentations are non-specific for bleomycin-induced lung injury (BILI), depending on the onset and severity of symptoms. There is no established guideline for the best treatment of DILI and the treatment is based on the time and severity of pulmonary symptoms. It is important to consider BILI in any patient with pulmonary clinical manifestations who has been treated with bleomycin.  Here, we report a 19-year-old woman who is a known case of Hodgkin lymphoma. She was treated with a bleomycin-containing chemotherapy regimen. On the 5th month of therapy, she was admitted to hospital with severe acute pulmonary symptoms and decreased oxygen saturation. She was treated successfully with high-dose corticosteroid without any significant sequelae.
کلیدواژه‌های انگلیسی مقاله Acute Lung Injury,Pulmonary,Bleomycin
نویسندگان مقاله Marziyeh Ghalamkari |
Department of Internal Medicine, School of Medicine, Iran University of Medical Sciences, Tehran, Iran

Mahdi Khatuni |
Department of Pulmonary Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran,

Gholamreza Toogeh |
Thrombosis Hemostasis Research Center, Tehran University of Medical Sciences, Tehran, Iran

Sepehr Haghighi |
Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran,

Maryam Taherkhani |
Department of Internal Medicine, Qazvin University of Medical Sciences, Qazvin, Iran

نشانی اینترنتی https://www.tanaffosjournal.ir/article_702007_c22472701d38e206d42f648da11556e2.pdf
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات