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Tanaffos، جلد ۲۲، شماره ۱، صفحات ۲۷-۳۹
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Plant-Derived Antioxidants for Management of COVID-19: A Comprehensive Review of Molecular Mechanisms |
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| چکیده انگلیسی مقاله |
We aimed to review the literature to introduce some effective plant-derived antioxidants to prevent and treat COVID-19. Natural products from plants are excellent sources to be used for such discoveries. Among different plant-derived bioactive substances, components including luteolin, quercetin, glycyrrhizin, andrographolide, patchouli alcohol, baicalin, and baicalein were investigated for several viral infections as well as SARS-COV-2. The mechanisms of effects detected for these agents were related to their antiviral activity through inhibition of viral entry and/or suppuration of virus function. Also, the majority of components exert anti-inflammatory effects and reduce the cytokine storm induced by virus infection. The data from different studies confirmed that these agents may play a critical role against SARS-COVID-2 via direct (antiviral activity) and indirect (antioxidant and anti-inflammatory) mechanisms, suggesting that natural products are a potential option for management of patients with COVID-19 due to the lower side effects and high efficiency. |
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| کلیدواژه‌های انگلیسی مقاله |
Coronavirus disease 2019,Angiotensin-Converting Enzyme2,Inflammation,Herbal Antioxidants,Antiviral |
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| نویسندگان مقاله |
Tahmineh Mokhtari |
Hubei Key Laboratory of Embryonic Stem Cell Research, Faculty of Basic Medical Sciences, Hubei University of Medicine, Shiyan 442000, Hubei, People’s Republic of China
Maryam Azizi |
Department of Anatomy, School of Medicine, Tehran Medical Sciences Branch, Islamic Azad University, Tehran, Iran
Fatemeh Sheikhbahaei |
Department of Anatomy, Afzalipour School of Medicine, Kerman University of Medical Sciences, Kerman, Iran
Hooman Sharifi |
Tobacco Prevention and Control Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran
Makan Sadr |
Virology Research Center, NRITLD, Shahid Beheshti University of Medical Sciences, Tehran, Iran
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| نشانی اینترنتی |
https://www.tanaffosjournal.ir/article_708459_4e94a10b3f376829e5c622d1405fb62c.pdf |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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| نوع مقاله منتشر شده |
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