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Middle East Journal of Cancer، جلد ۱۴، شماره ۴، صفحات ۴۸۱-۴۹۷
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
The Emerging Role of Chitosan-based Polymeric Nanoparticles in the Diagnosis and Treatment of Gynecological Cancers |
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| چکیده انگلیسی مقاله |
Breast and gynecological cancers are the most common malignancies in females. Early-stage detection and treatment could significantly reduce the mortality rate in patients. However, common treatments such as chemotherapy and radiotherapy fail after a while and lead to recurrence and drug resistance in cancer cells. The recent use of nanotechnology has enabled the development of novel approaches for diagnosing and treating oncological diseases. Chitosan-based polymer nanoparticles (CHPNPs) with unique properties such as non-toxicity, biocompatibility, and anti-carcinogenic effects are promising tools for the clinical development of targeted delivery systems. So far, various methods have been applied to use these nanoparticles in the diagnosis and treatment of various cancers. Identifying the most practical methods is one of the most important challenges in achieving effective treatments. A review of these studies can provide better horizons to realize effective treatment. In this review, we evaluate and discuss the use of CHPNPs from published literature to assess diagnostic and therapeutic strategies in breast and gynecological cancers, including ovarian and uterine neoplasms, as well as their advantages and challenges. |
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| کلیدواژه‌های انگلیسی مقاله |
Chitosan nanoparticles, Nanotechnology, Breast neoplasms, Ovarian neoplasms, Uterine Neoplasms |
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| نویسندگان مقاله |
Babak Arji Roudsari |
Department of Anatomical Sciences, Medical School, Kermanshah University of Medical Sciences, Kermanshah, Iran
Elham Arkan |
Nano Drug Delivery Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran
Cyrus Jalili |
Department of Anatomical Sciences, Medical School, Kermanshah University of Medical Sciences, Kermanshah, Iran
Kamran Mansouri |
Department of Molecular Medicine, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran
Mitra Bakhtiary |
Department of Anatomical Sciences, Medical School, Kermanshah University of Medical Sciences, Kermanshah, Iran
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| نشانی اینترنتی |
https://mejc.sums.ac.ir/article_49230_dcd23bee01ccd988c41ce6817a752d2b.pdf |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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