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Iranian Journal of Neonatology، جلد ۱۴، شماره ۱، صفحات ۴۶-۵۳
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Does Maternal Hemoglobin Consistently Associate with Iron Status at Birth? Evidence from a Cross-sectional Study in Indonesia |
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| چکیده انگلیسی مقاله |
Background: Maternal iron status is a vital determinant of feto-maternal iron transfer to ensure the adequacy of neonatal iron. Hemoglobin measurement is often used in pregnancy as an iron status parameter. However, evidence on the association between maternal hemoglobin and newborn iron status is still inconclusive. This study aims to assess the association between maternal hemoglobin and neonatal iron status.Methods: We conducted a cross-sectional study involving 84 neonates and their mothers in three hospitals in Central Java, Indonesia. Maternal hemoglobin was measured as a proxy for maternal iron status. Neonatal iron status was measured using hematologic markers (red blood cell count, hemoglobin, hematocrit, mean corpuscular volume, and red cell distribution) and biochemical markers (serum iron, soluble transferrin receptor/sTfR, and cord blood hepcidin). Neonatal iron status was compared between the two groups of maternal iron status followed by sensitivity analysis.Results: Maternal hemoglobin was not significantly associated with neonatal hematologic markers or biochemical markers. Sensitivity analysis did not reveal any associations in multiple tests conducted by various categories.Conclusion: Maternal hemoglobin was consistently not associated with neonatal iron status, as measured by both hematologic and biochemical markers. The use of maternal hemoglobin as a single parameter proxy for maternal and neonatal iron status is likely inaccurate and can potentially underestimate the actual maternal and neonatal iron status. |
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| کلیدواژه‌های انگلیسی مقاله |
Hemoglobin, Hepcidin, iron status, Maternal, Newborn, sTfR |
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| نویسندگان مقاله |
| Qodri Santosa
Department of Child Health, Faculty of Medicine, Universitas Jenderal Soedirman, Purwokerto, Indonesia
| Alfi Muntafiah
Department of Biochemistry, Faculty of Medicine, Universitas Jenderal Soedirman, Purwokerto, Indonesia
| Lantip Rujito
Department of Molecular Biology, Faculty of Medicine, Universitas Jenderal Soedirman, Purwokerto, Indonesia
| Joko Mulyanto
Department of Public Health and Community Medicine, Faculty of Medicine, Universitas Jenderal Soedirman, Purwokerto, Indonesia
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| نشانی اینترنتی |
https://ijn.mums.ac.ir/article_21697.html |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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| نوع مقاله منتشر شده |
تحقیقی اصیل |
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