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Infection Epidemiology and Microbiology، جلد ۹، شماره ۱، صفحات ۰-۰
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Diagnostic Role of Platelet-Lymphocyte Ratio and Platelet Parameters in COVID-19 Disease |
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| چکیده انگلیسی مقاله |
Aims: To analyze the utility of platelet parameters in assessing the severity in COVID-19 patients. Materials & Methods: Patients with RT-PCR confirmed COVID-19 in the Department of Pathology of a tertiary care hospital in south India, during the period from June 2020 to December 2020 were included in the study. The clinical details and laboratory parameters of these patients were obtained. The difference between the study variables was assessed using independent t-test. The optimum cut-off value of platelet–lymphocyte ratio (PLR) between the tested groups was estimated using ROC analysis. Findings: The study included 218 patients and 17.9% of them showed thrombocytopenia at the time of admission. Among the hematological parameters, PLR, Absolute lymphocyte count (ALC), Platelet Distribution Width (PDW), D-dimer and Erythrocyte Sedimentation Rate (ESR) were significantly different between ICU and non-ICU groups. Increased PLR value was associated with severe disease. Conclusion: PLR can be used as an additional biomarker in assessing the severity of COVID-19 disease and a cut-off value of 210.27 is optimal to differentiate severe COVID-19 disease from mild and moderate forms with 79% specificity. |
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| کلیدواژه‌های انگلیسی مقاله |
Biomarker, COVID-19, Intensive care unit |
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| نویسندگان مقاله |
| Nidhya Ganesan
Associate Professor, Department of Pathology, PSG Institute of Medical Sciences and Research, Coimbatore, India
| Eliz Thomas
Assistant Professor, Department of Pathology, PSG Institute of Medical Sciences and Research, Coimbatore, India
| Subba Rao tadury Madhukar
Professor, Department of Pathology, PSG Institute of Medical Sciences and Research, Coimbatore, India
| Karthikeyan S
Associate Professor, Department of Community Medicine, PSG Institute of Medical Sciences and Research, Coimbatore, India
| Lawanya G
Assistant Professor, Department of Pathology, PSG Institute of Medical Sciences and Research, Coimbatore, India
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| نشانی اینترنتی |
http://iem.modares.ac.ir/browse.php?a_code=A-10-72818-1&slc_lang=en&sid=4 |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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