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Journal of Nanostructures، جلد ۱۱، شماره ۴، صفحات ۶۴۷-۶۵۳
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عنوان انگلیسی Effect of free Prodigiosin pigment and mixed Prodigiosin with TiO2 nanoparticles in some viable organs of white mice
چکیده انگلیسی مقاله The study evaluated the effect of TiO2 NPs mixed with pigment on liver and kidney weight. Liver weight in G1, which is administrated with low dose of prodigiosin decreased significantly compared to liver weight in control group. No significant differences were found in kidney weight between the study groups in comparison with the control. The results also, showed highly significant increase in the level of GOT enzyme in G3, G4, G5 and G. This may confirm the effect of TiO 2 NPs in restricting the prodigioisin effect and increasing its toxicity. All the study groups showed highly significant increase in urea level when compared to its level in the control group. G1, which is administrated with low dose of prodigiosin showed the highest urea levels among other groups. Same thing about GPT enzyme level, in G1 and G2 become less in a significant way than its level in the control group. The cytotoxic effects of TiO2 NPs increased when the dose was raised, according to the results of this investigation. However, the presence of Prodigiosin inhibits the activity of nanoparticles and reduces their negative effects in essential organs (liver and kidney).
کلیدواژه‌های انگلیسی مقاله free Prodigiosin, mixed, TiO2 nanoparticles in, some viable, white mice
نویسندگان مقاله Shaima R. Ibraheem |
Collage of Science/ Baghdad University/Biotechnology dep. Iraq

Muntaha R. Ibraheem |
Alkawarizmi Collage of engineering /Baghdad University/ Biomedical dep. Iraq

Marwa Shakir |
Collage of Science/ Baghdad University/Biotechnology dep. Iraq

Ghada Sabeeh |
Collage of Science/ Baghdad University/Biotechnology dep. Iraq

نشانی اینترنتی https://jns.kashanu.ac.ir/article_111545_7891ea28c69a8ad18a9acf333daf53d4.pdf
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