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Journal of Nanostructures، جلد ۱۲، شماره ۳، صفحات ۷۷۱-۷۷۳
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عنوان انگلیسی Inhibitory Effect of ZrO2NPs on Candida Albicans in Heat-Cured Acrylic-Based Soft Lining Material
چکیده انگلیسی مقاله The most prevalent issue that can contribute to persistent mucosal inflammation is the development of microorganisms and fungi, particularly Candida Albicans (C. albicans), on soft denture lining material. The objective of the current study is to identify the inhibitory effect of Zirconium Oxide Nanoparticles (ZrO2NPs) on C. albicans in heat-cured acrylic-based soft lining material and the quantity of zirconium ions (Zr) released by the composite of soft liner and ZrO2NPs. Soft denture liners made of acrylic were given varied ratios of ZrO2NPs. According to the test that will be conducted, 200 samples were separated into two groups (experimental and control). The soft liner/ZrO2NPs composite’s antifungal activity was evaluated utilizing two techniques over three distinct time periods (disk-diffusion test and viable count of C. albicans). Atomic Absorption Spectroscopy (AAS) was used to measure the amount of Zr emitted in synthetic saliva over two separate time periods. The strength of the soft liner’s shear bond to the denture base material made of acrylic was evaluated using an Instron testing equipment. Compared to the control group, there was a highly significant drop in C. albicans colony forming units in the experimental groups (1.5% and 2% ZrO2NPs). Once ZrO2NPs were added to soft liners at a rate of 2%, the shear bonding strength’s mean value increased in a manner that was highly significant. As a result of this research, ZrO2NPs could be incorporated into acrylic-based soft denture lining materials to give them antifungal qualities, which lower the risk of developing denture-induced stomatitis.
کلیدواژه‌های انگلیسی مقاله Antifungal activity, Candida albicans, Zirconium oxide nanoparticles
نویسندگان مقاله Amir Fadhil Al-Tu’ma |
Ahl Al Bayt University, College of MLT, Kerbala, Iraq

Zeena Dhubyan Mohammed Zaki |
Department of Dentistry, AlNoor University College, Bartella, Iraq

Randa Ahmed |
College of Medical Technology/ Al-Farahidi University, Iraq

Sarah Kamil Abbood |
Medical laboratory Techniques Department, AL-Mustaqbal University College, Iraq

Ali Abdul Kadhim Ruhaima |
AL-Nisour University College, Baghdad, Iraq

Zainab Jamal Hamoodah |
Mazaya University College, Iraq

Ahmed S. Abed |
Department of Prosthetic Dental Technology, Hilla University college, Babylon, Iraq

Irina V. Pavlova |
Belgorod State National Research University, 85, Pobedy St, Belgorod, 308015, Russian Federation

نشانی اینترنتی https://jns.kashanu.ac.ir/article_112822_0e4eeed44f8627afeb91dcbdcb4cbfb9.pdf
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