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Iranian Journal of Neonatology، جلد ۱۳، شماره ۲، صفحات ۱۲۵-۱۲۹
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Aplasia Cutis Congenita Associated with the Use of Antithyroid Medications during Pregnancy: A Case Report |
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| چکیده انگلیسی مقاله |
Background: Aplasia Cutis Congenita (ACC) is a rare malformation characterized by localized congenital absence of the skin which was first described by Cordon in 1767. ACC is estimated to occur in approximately 1 to 3 cases in 10000 live births. Many factors can contribute to developing ACC among which antithyroid medications were the strongest risk factor. A total of 61 cases of ACC were reported due to Methimazole/Carbimazole.Case report: We report a female infant with ACC whose mother received Methimazole during pregnancy. Two small, punch-out lesions of the scalp were observed in diameters from 1.5 cm to 2 cm. The patient was treated with conservative care. Crusting and scab formation began on the fifth day. Minor, atrophied and hairless scars were found at the previous location of lesions by reexamining after 12 months.Conclusion: The etiology of ACC has not yet been clearly defined. Methimazole may be a factor associated with this disorder. Management of ACC includes conservative care and surgery depending on the location and size of lesions, associated anomalies, and health of the infant. |
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| کلیدواژه‌های انگلیسی مقاله |
Antithyroid medications, Aplasia Cutis Congenita, Carbimazole, Methimazole, pregnancy |
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| نویسندگان مقاله |
| Pham Chi Kong
Department of Delivery, Vice-Director of Da Nang Hospital for Women and Children, 402 Lê Văn Hiến, Khuê Mỹ, Ngũ Hành Sơn, Đà Nẵng, Vietnam
| Huynh Nhat
Department of Gynecology, Da Nang Hospital for Women and Children, 402 Lê Văn Hiến, Khuê Mỹ, Ngũ Hành Sơn, Đà Nẵng, Vietnam
| Le Chi
Department of Dermatology, Đà Nẵng C Hospital, 122 Hải Phòng, Thạch Thang, Hải Châu, Đà Nẵng, Vietnam
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| نشانی اینترنتی |
https://ijn.mums.ac.ir/article_19786.html |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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| نوع مقاله منتشر شده |
گزارش موارد نادر |
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